摘要
儿童特发性心肌病(idiopathic cardiomyopathy,ICM)是一种罕见病,终末期表现为心泵功能衰竭,多数患儿预后不佳。目前对于儿童ICM的终末期管理主要包括以改善心力衰竭为目的的药物治疗和心脏移植两个方面。部分患儿因供心短缺或不符合移植条件而死亡。机械循环支持可改善部分终末期ICM患儿预后,但尚未在国内儿童ICM患者中推广应用。本文以目前国内外儿童ICM及儿童心力衰竭诊治指南为参考,对特发性心肌病不同临床表型终末期血流动力学特点进行分析,结合近年机械循环支持研究进展,对儿童ICM终末期机械循环治疗的相关内容进行综述,为ICM的治疗提供新思路。
Idiopathic cardiomyopathy(ICM)is a rare pediatric disease with a poor prognosis.Current end-stage management of ICM is composed mostly of routine correcting heart failure(HF)and heart transplantation(HT).Some individuals die from a shortage of donor heart or non-suitability for HT.Mechanical circulation supports might improve the prognosis of end-stage patients.However,their applications have not been implemented for ICM children in China.Based upon current management guidelines for HF children,recent research advances of mechanical circulation support were summarized for optimal end-stage treatments of ICM children.
作者
孙鸣蔚
杨丽君
林茹
Sun Mingwei;Yang Lijun;Lin Ru(Department of Cardiopulmonary Bypass&Extracorporeal Membrane Oxygenation,Affiliated Children's Hospital,Zhejiang University School of Medicine,Hangzhou 310052,China)
出处
《临床小儿外科杂志》
CAS
CSCD
2023年第5期436-442,共7页
Journal of Clinical Pediatric Surgery
基金
国家中心自主设计项目(T21D0001)
关键词
扩张型心肌病
心力衰竭
血液循环
外科手术
儿童
Cardiomyopathy,Dilated
Heart Failure
Blood Circulation
Surgical Procedures,Operative
Child
作者简介
通信作者:林茹,Email:linru.008@zju.edu.cn.
