摘要
Esophageal cancer(EC)is one of the most common aggressive malignant tumors in the digestive system with a severe epidemiological situation and poor prognosis.The early diagnostic rate of EC is low,and most EC patients are diagnosed at an advanced stage.Multiple multimodality treatments have gradually evolved into the main treatment for advanced EC,including surgery,chemotherapy,radiotherapy,targeted therapy,and immunotherapy.And the emergence of targeted therapy and immunotherapy has greatly improved the survival of EC patients.This review highlights the latest advances in targeted therapy and immunotherapy for EC,discusses the efficacy and safety of relevant drugs,summarizes related important clinical trials,and tries to provide references for therapeutic strategy of EC.
基金
supported by grants from the National Natural Science Foundation of China(No.82002619)
the Key Medical Research Projects of Shanxi Province(No.2020XM55)
the Talent Introduction Scientific Research Start-up Fund of Shanxi Bethune Hospital(No.2020RC006)
the special fund for Science and Technology Innovation Teams of Shanxi Province(No.202204051001031)
Fundamental Research Program of Shanxi Province(No.202203021222349)
作者简介
Correspondence to:Dr.Wenhui Yang,Department of Gastroenterology,Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital,Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University,Taiyuan,Shanxi 030001,China,E-Mail:yangwenhui-10012@163.com
