摘要
目的了解云南省建水县、镇雄县成人及孕妇碘营养状况。方法2021年5-8月,在云南省建水县、镇雄县各选择1个城区和1个农村地区作为调查点。每个调查点选取至少100名成人(男女各半)和100名孕妇作为调查对象,采集所有调查对象1次随机尿样,检测尿碘、尿肌酐和尿钠含量;采集所有孕妇静脉血血样,检测血清碘含量,并采用百分位数法建立孕妇血清碘95%医学参考值范围。结果建水县和镇雄县成人尿碘中位数为184.7μg/L(n=432),尿肌酐中位数为12355.0μmol/L(n=431),尿钠中位数为156.5 mmol/L(n=420)。建水县成人尿碘中位数高于镇雄县(197.3比170.2μg/L),差异有统计学意义(Z=-2.90,P=0.003)。建水县和镇雄县孕妇血清碘中位数为92.1μg/L(n=412),血清碘95%医学参考值范围为45.3~183.5μg/L;孕妇尿碘中位数为138.6μg/L(n=413),尿肌酐中位数为12173.0μmol/L(n=408),尿钠中位数为152.2 mmol/L(n=409)。建水县孕妇尿碘(154.1比115.8μg/L)、尿肌酐(13216.0比11376.0μmol/L)和尿钠中位数(161.8比141.8 mmol/L)均高于镇雄县,差异均有统计学意义(Z=-5.12、-2.29、-4.30,均P<0.05)。结论建水县和镇雄县成人均处于碘适宜水平,但镇雄县孕妇处于碘缺乏水平。
Objective To investigate the iodine nutritional status of adults and pregnant women in Jianshui County and Zhenxiong County,Yunnan Province.Methods From May to August 2021,one urban area and one rural area in Jianshui County and Zhenxiong County,Yunnan Province were selected as investigation sites.At least 100 adults(half male and half female)and 100 pregnant women were selected as survey subjects in each investigation site.Random urine samples were collected from all survey subjects once to detect urine iodine,creatinine and sodium contents.Venous blood samples of all pregnant women were collected to detect the serum iodine content,and the 95%medical reference range of serum iodine was established using the percentile method.Results The medians urinary iodine,creatinine and sodium of adults in Jianshui County and Zhenxiong County were 184.7μg/L(n=432),12355.0μmol/L(n=431)and 156.5 mmol/L(n=420),respectively.The median urinary iodine of adults in Jianshui County was higher than that in Zhenxiong County(197.3 vs 170.2μg/L),the difference was statistically significant(Z=-2.90,P=0.003).The median serum iodine of pregnant women in Jianshui County and Zhenxiong County was 92.1μg/L(n=412),with a 95%medical reference value ranged from 45.3 to 183.5μg/L;the medians urinary iodine,creatinine and sodium of pregnant women were 138.6μg/L(n=413),12173.0μmol/L(n=408)and 152.2 mmol/L(n=409),respectively.The urinary iodine(154.1 vs 115.8μg/L),urinary creatinine(13216.0 vs 11376.0μmol/L)and urinary sodium(161.8 vs 141.8 mmol/L)of pregnant women in Jianshui County were higher than those in Zhenxiong County,with statistical differences(Z=-5.12,-2.29,-4.30,P<0.05).Conclusion Adults in Jianshui County and Zhenxiong County are at an appropriate level of iodine,but pregnant women in Zhenxiong County are at an iodine deficiency level.
作者
李加国
吴鹤松
叶枫
赵志花
史亮晶
陈黎
董万贤
杨伟
邓春元
Li Jiaguo;Wu Hesong;Ye Feng;Zhao Zhihua;Shi Liangjing;Chen Li;Dong Wanxian;Yang Wei;Deng Chunyuan(Department for Endemic Disease Prevention and Control,Yunnan Institute for Endemic Disease Control and Prevention,Dali 671000,China;Department for Endemic Disease Prevention and Control,Honghe Prefecture Center for Disease Control and Prevention,Mengzi 661100,China;Department for Endemic Disease Prevention and Control,Zhaotong Center for Disease Control and Prevention,Zhaotong 657000,China;Department for Endemic Disease Prevention and Control,Jianshui Center for Disease Control and Prevention,Jianshui 654300,China;Department for Endemic Disease Prevention and Control,Zhenxiong Center for Disease Control and Prevention,Zhenxiong 657200,China)
出处
《中华地方病学杂志》
CAS
北大核心
2023年第10期803-807,共5页
Chinese Journal of Endemiology
关键词
碘
尿
血
成人
孕妇
Iodine
Urine
Blood
Adults
Pregnant women
作者简介
通信作者:李加国,Email:leejg66@163.com
