摘要
特发性脊柱侧弯(idiopathic scoliosis,IS)作为儿童青少年常见的脊柱疾病之一,影响因素复杂,给儿童青少年的生活质量和身心健康带来严重影响。雌激素作为影响特发性脊柱侧弯发生、发展的一个重要因素,可通过异常调节骨代谢、经受体作用于椎旁肌肉等直接或间接影响脊柱侧弯的发生、发展。研究雌激素对脊柱侧弯进展的影响,可为脊柱侧弯病因研究和治疗提供新的策略。本文就雌激素与特发性脊柱侧弯相关性的研究进展进行综述。
As one of common spinal diseases in children and adolescents,idiopathic scoliosis(IS)has so many complex influencing factors as to seriously affect the quality of life and physical and mental health.Estrogen may directly or indirectly modulate the occurrence and development of IS through abnormal regulations of bone metabolism and its effect on paravertebral muscles via receptors.Elucidating the underlying mechanism offers a novel therapeutic strategy.This review summarized the latest researches on correlation between estrogen and IS.
作者
王培鑫
赵军
王兴盛
徐世红
姜朝阳
王小强
杨红娟
Wang Peixin;Zhao Jun;Wang Xingsheng;Xu Shihong;Jiang Zhaoyang;Wang Xiaoqiang;Yang Hongjuan(Clinical College of Traditional Chinese Medicine,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Trauma Centre,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China)
出处
《临床小儿外科杂志》
CAS
CSCD
北大核心
2024年第5期493-495,共3页
Journal of Clinical Pediatric Surgery
基金
省级重点人才项目(甘组通字【2022】77号)
联合科研基金重大项目(23JRRA1529)
临床医学研究中心建设项目(21JR7RA681)
关键词
雌激素
脊柱疾病
外科手术
儿童
Estrogens
Spinal Diseases
Surgical Procedures,Operative
Child
作者简介
通信作者:赵军,Email:673078008@qq.com.
