摘要
支气管肺发育不良症(bronchopulmonary dysplasia,BPD)是早产儿、尤其是小早产儿呼吸系统常见疾病,具有独特的临床、影像学及组织学特征.目前其确切的病因和发病机制尚不明确,无特效治疗方法.现有的研究主要以筛选出高危儿及预防为主,其中预测BPD的可能生物标志物是研究重点.该文就近年来国内外对血液中BPD预测的生物标志物作一综述.
Bronchopulmonary dysplasia(BPD)is a common respiratory disease among preterm infants,especially among little premature infants.BPD has unique clinical,imageology and histological features.The exact etiology and pathogenesis of BPD remain unclear in current studies and there are no effective treatments.Current studies mainly focus on high-risk infants screening examination and its prevention.Predicting possible biomarkers of BPD is a research focus.This article reviews the biomarkers predicted by BPD in blood at home and abroad in recent years.
作者
丁利(综述)
朱雪萍(审校)
Ding Li(Department of NeonatOLOGY,Children's Hospital of Soochow University,Suzhou215025,China)
出处
《国际儿科学杂志》
2018年第12期941-944,共4页
International Journal of Pediatrics
基金
国家自然基金面上项目(81771626)
江苏省卫生健康委员会妇幼健康重点人才项目(FRC201731)
苏州市卫生健康委员会重点病种诊疗技术项目(LCZX201612)
苏州市科学技术局和财政局民生科技-关键技术应用研究项目(SS201644)
苏州市科学技术局和财政局科技发展计划项目(SS201428)National Natural Science Foundation Project(81771626)
Jiangsu Commission of Health Women and Children Health Key Talent Project(FRC201731)
Suzhou Commission of Health Key Disease Diagnosis and Treatment Technology Project(LCZX201612)
Bureau of Science and Technology of Suzhou and Bureau of Finance of Suzhou People's Livelihood Science and Technology-Key Technology Application Research Project(SS201644)
Science and Technology Development Project(SS201428).
关键词
支气管肺发育不良
早产儿
标志物
预测
Bronchopulmonary dysplasia
Preterm infants
Biomarker
Prediction
作者简介
通信作者:朱雪萍,Email:zhuxueping4637@hotmail.com
