摘要
IntroductionRosai-Dorfman disease (RDD),also called sinus histiocytosis with massive lymphadenopathy,is a rare,benign,idiopathic histiocytic proliferative disease.It is characterized by painless massive cervical lymphadenopathy.Additional symptoms may include fever,leukocytosis,polyclonal hypergammaglobulinemia,and an increased erythrocyte sedimentation rate.Cutaneous RDD (CRDD) is confined to the skin with no lymphadenopathy or other simultaneous phenomena.1-2 Pure CRDD accounts for only 3% of all described cases of RDD.3 We herein report an atypical case of CRDD in a woman with multiple nodules in the thighs and buttocks,which may improve the knowledge of this disease.
基金
supported by Natural Science Foundation of China(No.81572680 and No.81673043)
作者简介
Corresponding author:Prof.Cheng-Xin Li,Department of Dermatology,PLA General Hospital,Beijing 100853,China,E-mail:chengxinderm@163.com