摘要
目的 观察心理干预对神经病理性疼痛患者疼痛、焦虑以及抑郁情绪的影响,从而探讨心理干预在神经病理性疼痛治疗中的作用.方法 选择2017年6月至2017年12月在西南医科大学附属中医医院疼痛科住院的神经病理性疼痛(带状疱疹后神经痛和三叉神经痛)患者60例,随机分为心理干预组和常规治疗组各30例.常规治疗组在DSA引导下行神经阻滞与加巴喷丁治疗,心理干预组在此基础上,实施心理干预治疗.于治疗前及治疗后1、2、4周时分别测试疼痛视觉模拟评分(VAS)、焦虑评分(SAS)和抑郁评分(SDS)评价患者疼痛及情绪状况;同时在各时间点抽取外周静脉血检测皮质醇(Cor)浓度.结果 两组患者均完成研究与随访,治疗前两组患者SAS、SDS、VAS评分及Cor水平差异均无统计学意义(P>0.05).两组VAS、SAS、SDS评分及Cor水平治疗后1、2、4周时均较治疗前明显降低,差异有统计学意义(P<0.05).治疗后1、2、4周时,心理干预组VAS、SAS、SDS评分及Cor水平均低于常规治疗组,差异有统计学意义(P<0.05).结论 在神经病理性疼痛治疗中,心理干预能够改善焦虑抑郁的负性情绪,对疼痛的缓解具有促进作用.
Objective To observe the effects of psychological intervention treatment on anxiety,depression,and the pain intensity for patient with neuropathic pain,thus to explore the role of psychological intervention on neuropathic pain.Methods Sixty patients with neuropathic pain(postherpetic neuralgia and trigeminal neuralgia)from June 2017 to November 2017 in Hospital(T.C.M)Affiliated to Southwest Medical University were randomly divided into two groups,thirty cases in each group.Patients were treated with gabapentin therapy and DSA guided nerve block in routine therapy group,and psychological intervention was added in psychological intervention group.The visual analogue score(VAS),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were tested and recorded before treatment and at 1 week,2 weeks and 4 weeks after treatment respectively to evaluate patients'pain intensity and emotional state.The intravenous concentration of cortisol(Cor)was detected at each time point.Results All patients finished the test and had followed-up visit.There was no statistical difference in SAS,SDS,VAS and Cor before the treatment between the two groups(P>0.05).In both groups,VAS,SAS,SDS and Cor levels at 1 week,2 weeks and 4 weeks were lower as compared with pretreatment,with statistical differences(P<0.05).VAS,SAS,SDS and the concentration of Cor in psychological intervention group at 1 week,2 weeks and 4 weeks after treatment were lower than those in routine therapy group,with statistical differences(P<0.05).Conclusion Psychological intervention can improve the negative emotions of anxiety and depression and promote the improvement of pain for the patients with neuropathic pain.
作者
边疆
张英
刘庆
Bian Jiang;Zhang Ying;Liu Qing(Department of Anesthesiology,Hospital(T.C.M)Affiliated to Southwest Medical University,Luzhou City,Sichuan Province 646600,China)
出处
《实用疼痛学杂志》
2018年第5期367-374,共8页
Pain Clinic Journal
关键词
神经病理性疼痛
心理干预
焦虑
抑郁
Neuropathic pain
Psychological intervention treatment
Anxiety
Depression
作者简介
通信作者:刘庆,Email:1105859368@qq.com
