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新辅助化疗方案在乳腺癌治疗中的应用观察效果

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摘要 目的:探讨新辅助化疗方案在乳腺癌治疗中的临床效果。方法选取我院2011年1月~2013年6月收治的乳腺癌患者92例,随机分为观察组和对照组(46例),观察组给予环磷酰胺(600mg/m2)+表柔比星(70 mg/m2)+多西他赛(175 mg/m2)化疗方案,对照组给予表阿霉素(60 mg/m2)+环磷酰胺(500 mg/m2)+氟尿嘧啶(500 mg/m2)化疗方案。3w为一个疗程,2个疗程后对治疗效果进行评价。结果观察组患者总有效率为91.3%(42/46),对照组患者的总有效率为71.7%(33/46)且差异比较有统计学意义(χ2=5.84,P=0.02);治疗后治疗组CEA(P=0.002,t=-3.13)、CA-153(P<0.001,t=-6.36)水平显著低于对照组;治疗组毒副反应少于对照组。结论新辅助化疗方法对于乳腺癌患者的化疗效果明显,值得推广应用。
作者 曾维英
出处 《医学信息(医学与计算机应用)》 2014年第7期179-179,共1页 Medical Information
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