期刊文献+

人类免疫缺陷病毒感染机会性感染和菌群分布特点分析 被引量:1

在线阅读 下载PDF
导出
摘要 目的:分析HIV-1感染机会性感染和菌群分布特点。方法抽取本院2013年1月~2014年3月收治的38例 HIV-1患者,于患者入院时使用 FACScan流式细胞仪检测外周血 CD4+细胞数及在艾迪康公司协助下,采用RT-PCR检测血浆HIV-1病毒载量,机会性感染以出院诊断为准,全部患者均按照临床表现及实验室检查进行确诊。结果8例患者一共有12例患者发生过机会性感染,其中有5例次是二重或者多重感染,机会性感染患者外周血 CD4+细胞数比无机会性感染者低,但机会性感染者外周 CD4+平均病毒载量明显比无机会性感染者高,两者存在明显差异性(P<0.01),其中呼吸道、消化道及血液系统是最容易发生感染的部位。结论 HIV-1感染者机会感染的发生率及病死率较高,在初期应采取有效措施进行预防。
出处 《医学信息(医学与计算机应用)》 2014年第29期247-248,共2页 Medical Information
  • 相关文献

参考文献2

二级参考文献16

  • 1U. S. Public Health Service(USPHS) and Infectious Disease Society of America( IDSA). 2001 USPHA/IDSA guidelines for the prevention of opportunistic infected with human immunodeficiency virus [ J ].MMWR,2001,1 - 68.
  • 2Burman W, El-Sadr WE, Matts J, et al. Continued low rates of Mycobacterium avium complex and bacterial pneumonia despite withdrawal of azithromycin prophylaxis among patients with CD4^+ cell rebound[A]. Program and abstracts of the 9th Conference on Retroviruses and Opportunictic Infections [ C]. Seattle, Washington, February 24 -28,2002,631.
  • 3Yangco BG, Von Bargen JC, Moorman AC, et al. Can PCP prophylaxis be safely discontinued among clinically improving HIV patients[ C] ?[ Abstract I - 262 ]. 38th ICAAC, San Diego, CA, 1998.
  • 4Anglaret X, Chene G, Attia A, et al Early chemotherapy with trimethoprin-sulphamethoxazole for HIV-1 infected adults in Abidjan,Cote d' Ivoire: a randomised control trial[J ]. Lancet, 1999,353:1463-1468.
  • 5Wiktor SZ Morokro MS, Grant AD, et al. Efficacy of trimethoprin-sulphamethoxazole prophylaxis to decrease morbidity and mortality in HIV-linfected patients with tuberculosis in Adidjan, Cote d' Ivoire: a randomised control trial [J ]. Lancetl, 999,353:1469 - 1474.
  • 6Mellors JW, Munoz A, Giogi TV. et al. Plasm viral load and CD4^+ lymphacytes as prognostic markers of HIV-1 infection[J ]. Ann Intern Med,1997,126:946- 954.
  • 7Tansuphasawedikul S, Amornkul PN, Tanchanpong C, et al. Clinical presentation of hospitalized adult patients with HIV infection and AIDS in Bangkok,Thailand[J] .Acquir Immune Defic Syndr, 1999,21(4) :326 - 332.
  • 8Chariyalertsak S, Sirisanthana T, Sa ngwonloey O, et al. Clinical presentation and risk behaviors of patients with acquired mmunodeficiency syndrome in Thailand, 1994-1998: regional variation and temporal trends. [J] .Clin Infect Dis,2001,32(6) :955 - 962.
  • 9U. S. Public Health Service(USPHS) and Infectious Disease Society of America( IDSA). 1999 USPHA/IDSA guidelines for the prevention of opportunistic infected with human immunodeficiency virus[J]. MMRW, 1999,48:1 - 66.
  • 10Badri M, Ehrlich R, Wood R, et al. Initiating cotriimoxazole prophylaxis in HIV-infected patients in Africa: an evaluation of the provisional WHO/UNAIDS recommendations [ J ] . AIDS, 2001,15: 1143-1148.

共引文献95

同被引文献13

引证文献1

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部