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磁敏感加权成像在帕金森病中的应用研究 被引量:1

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摘要 目的:探究磁敏感加权成像(susceptibility weighted imaging,SWI)在帕金森病(Parkinson's disease,PD)中的临床应用价值。方法回顾性分析2010年6月~2013年7月于我院神经内科就诊的36例帕金森病患者的临床资料,同时选择同期年龄相近的健康体检者30例作为对照组,在GE 1.5T磁共振成像系统上实行常规头颅磁共振成像后,再实行磁敏感加权成像.经过SWI后处理软件得出相位图像后,在图像上手工绘制感兴趣区,测量黑质网状带、黑质致密带以及壳核的信号值。结果 PD组患者和正常对照组对比,黑质致密带、壳核的信号值差异有统计学意义(<0.05)。PD组患者黑质网状带及壳核铁沉积增加。PD组壳核的相位值与PD病程之间存在负相关。对照组中尾状核头、壳核、黑质相位值左侧低于右侧。结论利用SWI测定黑质致密带、苍白球的铁含量在PD诊断中具有临床应用价值,能够反映PD病情严重程度。
作者 赵望
出处 《医学信息(医学与计算机应用)》 2014年第21期118-119,共2页 Medical Information
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