摘要
目的分析探究阿托伐他汀联合曲美他嗪在冠心病治疗中的康复效果.方法该次将该院在2019年1—12月收治的冠心病患者一共80例作为研究的对象,基于平行、单盲、随机对照设计原则,将其分为两组,每组40例.常规治疗基础上,对照组应用曲美他嗪,观察组联合应用阿托伐他汀、曲美他嗪,对比两组临床疗效.结果(1)治疗后,观察组的冠心病发作频次为(2.18±1.06)次/周,持续时间为(3.24±0.81)min/次,对照组冠心病发作频次为(3.50±1.42)次/周,持续时间为(5.10±0.92)min/次,均大于观察组,两组数据差异有统计学意义(t=5.382、6.127,P<0.05).(2)观察组治疗总有效率的97.50%,明显高于对照组的80.00%(P<0.05).(3)治疗前,两组在TC、TG、LDL-C、HDL-C水平方面差异无统计学意义(P>0.05),治疗后观察组TC为(2.14±0.36)mmol/L,TG为(1.32±0.05)mmol/L,LDL-C为(1.51±0.27)mmol/L,HDL-C为(1.77±0.25)mmol/L,对照组TC为(3.10±0.78)mmol/L,TG为(1.67±0.18)mmol/L,LDL-C为(2.14±0.43)mmol/L,高于观察组,HDL-C为(0.98±0.32)mmol/L,低于观察组,两组数据差异有统计学意义(P<0.05).结论阿托伐他汀联合曲美他嗪治疗冠心病,康复疗效显著,可缓解病情发作,降低血脂水平,值得采纳应用.
Objective To analyze the rehabilitation effect of atorvastatin combined with trimetazidine in the treatment of coronary heart disease.Methods A total of 80 patients with coronary heart disease admitted to the hospital from January to December 2019 were divided into two groups based on the principle of parallel,single blind and randomized control design,40 cases in each group.On the basis of routine treatment,trimetazidine was used in the control group,and atorvastatin and trimetazidine were used in the observation group,and the clinical effects of the two groups was compared.Results 1.After treatment,the frequency of coronary heart disease attack in the observation group was(2.18±1.06)times/week,the duration was(3.24±0.81)min/time,the frequency of coronary heart disease attack in the control group was(3.50±1.42)times/week,the duration was(5.10±0.92)min/time,which were significantly higher than that in the observation group,and the data difference between the two groups was statistically significant(t=5.382,6.127,P<0.05).2.The total effective rate in the observation group was 97.50%,which was significantly higher than that of the control group(80.00%)(P<0.05).3.Before treatment,there was no significant difference in TC,TG,LDL-C,HDL-C levels between the two groups(P>0.05).After treatment,TC in the observation group was(2.14±0.36)mmol/L and TG was(1.32±0.05)mmol/L,LDL-C(1.51±0.27)mmol/L,HDL-C(1.77±0.25)mmol/L;control group TC(3.10±0.78)mmol/L,TG(1.67±0.18)mmol/L,LDL-C(2.14±0.43)mmol/L was higher than the control group,HDL-C(0.98±0.32)mmol/L was lower than the observation group.The data difference between the two groups was statistically significant(P<0.05).Conclusion Atorvastatin Combined with trimetazidine in the treatment of coronary heart disease has a significant rehabilitation effect,which can alleviate the attack of the disease and reduce the level of blood lipids,it is worthy of application.
作者
朱有兴
ZHU Youxing(The Second Department of Internal Medicine,Feixian People's Hospital,Linyi Shandong,273400,China)
出处
《反射疗法与康复医学》
2020年第11期85-87,共3页
Reflexology And Rehabilitation Medicine
关键词
阿托伐他汀
曲美他嗪
冠心病
康复效果
Atorvastatin
Trimetazidine
Coronary heart disease
Rehabilitation effect
作者简介
朱有兴(1965-),男,山东费县人,本科,副主任医师,研究方向:心血管内科。
