摘要
目的 探讨康复锻炼联合西药在高血压脑出血患者中的临床应用效果及对认知功能的影响.方法 选择2018年4月—2020年1月该院收治的高血压脑出血患者116例为研究对象,按照随机数字表法分为两组,每组58例.对照组采用地塞米松联合甘露醇治疗,观察组在对照组基础上联合康复锻炼.比较两组的神经功能缺损程度、日常生活能力、认知功能、生化指标水平及预后效果.结果 观察组干预后2周的美国国立卫生研究院卒中量表评分低于对照组,Barthel指数及简易精神状态检查表评分均高于对照组,组间差异有统计学意义(P<0.05).观察组干预后2周的S100B、神经元特异性烯醇化酶水平低于对照组,胰岛素样生长因子1水平高于对照组,组间差异有统计学意义(P<0.05).观察组治疗后的恢复良好率高于对照组,植物生存、偏瘫发生率及6个月死亡率均低于对照组,组间差异有统计学意义(P<0.05).结论 康复锻炼联合西药治疗高血压脑出血患者,有助于减轻神经功能缺损程度,提高患者日常生活能力,改善患者认知功能和生化指标.
Objective To explore the clinical application effect of rehabilitation exercise combined with western medicine in patients with hypertensive cerebral hemorrhage and the impact on cognitive function.Methods A total of 116 patients with hypertensive intracerebral hemorrhage admitted to the hospital from April 2018 to January 2020 were selected as the research objects,and they were divided into two groups with 58 cases in each group according to a random number table.The control group was treated with dexamethasone combined with mannitol,and the observation group was combined with rehabilitation exercises on the basis of the control group.The degree of neurological deficit,daily living ability,cognitive function,biochemical index level and prognostic effect were compared between the two groups.Results 2 weeks after the intervention,the National Institute of Health stroke scale scores of the observation group were lower than those of the control group,and the Barthel indicators and mini-mental state examination scores were higher than those of the control group,the difference between the groups was statistically significant(P<0.05).2 weeks after the intervention,the levels of S100B and neuron-specific enolase in the observation group were lower than those in the control group,and the levels of Insulin-like growth factor 1 was higher than that in the control group,the difference between the groups was statistically significant(P<0.05).The rate of good recovery after treatment in the observation group was higher than that of the control group,the survival rate of plants,the incidence of hemiplegia and the 6-month mortality rate were lower than those of the control group,the difference between the groups was statistically significant(P<0.05).Conclusion Rehabilitation exercise combined with western medicine to treat patients with hypertensive cerebral hemorrhage can help reduce the degree of neurological deficits,improve the patients'ability of daily living,and improve the patients'cognitive function and biochemical indicators.
作者
韩峰
HAN Feng(Department of Outpatient Westen Pharmacy,Anqiu Hospital of Traditional Chinese Medicine,Anqiu Shandong,262100,China)
出处
《反射疗法与康复医学》
2021年第14期65-67,共3页
Reflexology And Rehabilitation Medicine
关键词
高血压脑出血
康复锻炼
地塞米松
甘露醇
临床效果
认知功能
Hypertensive cerebral hemorrhage
Rehabilitation exercise
Dexamethasone
Mannitol
Clinical effect
Cognitive function
作者简介
韩峰(1981-),女,山东安丘人,本科,主管中药师,研究方向:高血压脑出血治疗。
