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子宫内膜息肉患者宫腔镜下息肉电切术后应用左炔诺孕酮宫内节育系统对子宫内膜厚度、月经恢复及疾病复发的影响 被引量:7

Effects of Levonorgestrel Intrauterine Contraceptive System on Endometrial Thickness, Menstrual Recovery and Disease Recurrence in Patients with Endometrial Polyps after Transcervical Resection of Myoma
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摘要 目的探讨子宫内膜息肉(EP)患者宫腔镜下息肉电切术(TCRP)后应用不同治疗方案对康复效果及疾病复发的影响.方法选取2019年1月—2020年5月于该院行TCRP的86例EP患者为研究对象,按术后治疗方式不同分为对照组与观察组,各43例.对照组术后口服地屈孕酮治疗,观察组术后采用左炔诺孕酮宫内节育系统治疗,随访至术后12个月.比较两组子宫内膜厚度、月经周期、经期、月经失血图(PBAC)评分、疾病复发情况、不良反应发生率.结果术前,两组子宫内膜厚度、月经周期、经期、PBAC评分比较,组间差异无统计学意义(P>0.05).术后12个月,两组子宫内膜厚度、经期、PBAC评分均优于术前,差异有统计学意义(P<0.05),但两组月经周期与术前比较,差异无统计学意义(P>0.05).术后12个月,观察组子宫内膜厚度(3.44±0.68)mm薄于对照组,PBAC评分(27.57±8.12)分低于对照组,组间差异有统计学意义(P<0.05),但两组月经周期、经期比较,组间差异无统计学意义(P>0.05).观察组复发率为2.33%,低于对照组的18.60%,差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论在EP患者TCRP术后应用左炔诺孕酮宫内节育系统的康复效果更佳,能够有效改善其月经经期紊乱、经量过多症状,降低疾病复发率,且安全性高. Objective To investigate the effect of different treatment regimens on rehabilitation effect and disease recurrence in patients with endometrial polyps(EP)after transcervical resection of myoma(TCRP).Methods A total of 86 EP patients who underwent TCRP in the hospital from January 2019 to May 2020 were selected as the research objects,and divided into control group and observation group according to different postoperative treatment methods,with 43 cases in each group.The control group was treated with oral dydrogesterone after operation,and the observation group was treated with levonorgestrel intrauterine contraceptive system after operation,and the follow-up was up to 12 months after operation.The endometrial thickness,menstrual cycle,menstrual period,pictorial blood loss assessment chart(PBAC)score,disease recurrence,and incidence of adverse reactions were compared between the two groups.Results Before surgery,there were no significant differences in endometrial thickness,menstrual cycle,menstrual period and PBAC score between the two groups(P>0.05).At 12 months after operation,the endometrial thickness,menstrual period and PBAC score of the two groups were better than those before operation,and the differences were statistically significant(P<0.05),but there was no significant difference in menstrual cycle between the two groups(P>0.05).At 12 months after operation,the endometrial thickness of the observation group(3.44±0.68)mm was thinner than that of the control group,and the PBAC score(27.57±8.12)was lower than that of the control group,and the differences between the groups were statistically significant(P<0.05),but there was no significant difference in the menstrual cycle and menstrual period between the two groups(P>0.05).The recurrence rate in the observation group was 2.33%,which was lower than 18.60%in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of levonorgestrel intrauterine contraceptive system in EP patients after TCRP has better rehabilitation effect,which can effectively improve the symptoms of menstrual disorder and excessive menstrual flow,reduce the recurrence rate of the disease,and has high safety.
作者 郭丰霞 GUO Fengxia(Department of Gynecology,Binzhou Second People's Hospital,Binzhou Shandong,256800,China)
出处 《反射疗法与康复医学》 2022年第10期155-158,共4页 Reflexology And Rehabilitation Medicine
关键词 子宫内膜息肉 宫腔镜下息肉电切术 地屈孕酮 左炔诺孕酮宫内节育系统 复发 Endometrial polyps Transcervical resection of myoma Didroxyprogesterone Levonorgestrel intrauterine contraceptive system Recrudescence
作者简介 郭丰霞(1974-),女,山东滨州人,本科,副主任医师,研究方向:妇科临床。
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