摘要
目的探讨通窍活血汤联合倍他司汀在椎基底动脉供血不足性眩晕(VBIV)中的临床效果.方法选取兰陵县人民医院2020年8月—2022年8月收治的82例VBIV患者为研究对象,按随机数字表法分为两组,每组41例.对照组采用倍他司汀治疗,观察组在此基础上采用通窍活血汤治疗,均持续14 d.比较两组患者的临床疗效、凝血功能、脑血流速度、眩晕障碍量表(DHI)评分及不良反应发生情况.结果观察组的治疗总有效率为95.12%,高于对照组的80.49%,差异有统计学意义(P<0.05).治疗14d后,观察组的活化部分凝血活酶时间、凝血酶原时间均长于对照组,组间差异有统计学意义(P<0.05).治疗14d后,观察组的左侧椎动脉、右侧椎动脉、基底动脉平均血流速度均快于对照组,组间差异有统计学意义(P<0.05).治疗14d后,观察组的DHI评分为(12.34±1.35)分,低于对照组的(15.28±1.44)分,差异有统计学意义(P<0.05).两组的不良反应发生率比较,差异无统计学意义(P>0.05).结论通窍活血汤联合倍他司汀可提高VBIV患者的治疗效果,改善其凝血功能,提升脑血流速度,降低DHI评分,安全可靠,值得临床推广使用.
Objective To investigate the clinical effect of Tongqihuoxue Decoction combined with betahistine in vertebral basilar insufficiency vertigo(VBIV).Methods 82 VBIV patients admitted to Lanling County People's Hospital from August 2020 to August 2022 were selected as the research objects and were divided into two groups according to random number table method,with 41 cases in each group.The control group was treated with betahistine,and the observation group was treated with Tongqiao Huoxue Decoction on this basis.Both groups were treated for 14 days.The clinical efficacy,coagulation function,cerebral blood flow velocity,dizziness handicap inventory(DHI)score the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.12%,which was higher than 80.49%of the control group,the difference was statistically significant(P<0.05).After 14 days of treatment,the activated partial thromboplastin time and prothrombin time in the observation group were longer than those in the control group,and the differences between the groups were statistically significant(P<0.05).After 14 days of treatment,the average blood flow velocity of the left vertebral artery,right vertebral artery and basilar artery in the observation group were faster than those in the control group,and the differences between the groups were statistically significant(P<0.05).After 14 days of treatment,the DHI score of the observation group was(12.34±1.35)points,lower than(15.28±1.44)points of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Tongqiao Huoxue Decoction combined with betahistine can improve the therapeutic effect of VBIV patients,improve their coagulation function,increase cerebral blood flow velocity,reduce DHI score,safe and reliable,worthy of clinical promotion.
作者
赵宇
ZHAO Yu(Department of Traditional Chinese medicine,Lanling County People's Hospital,Linyi Shandong,277600,China)
出处
《反射疗法与康复医学》
2023年第8期26-28,35,共4页
Reflexology And Rehabilitation Medicine
关键词
眩晕
椎基底动脉供血不足
通窍活血汤
倍他司汀
凝血功能
Vertigo
Vertebral basilar insufficiency
Tongqiao Huoxue Decoction
Betastatin
Coagulation function
作者简介
赵宇(1974-),男,山东临沂人,本科,副主任医师,研究方向:中西医结合治疗脑病。
