摘要
目的探究经皮穿刺微球囊压迫术及微血管减压术治疗三叉神经痛的效果。方法选择商河县人民医院2022年1月—2023年1月收治的84例三叉神经痛患者为研究对象,按照随机数字表法分为对照组及观察组,每组42例。对照组行微血管减压术,观察组行经皮穿刺微球囊压迫术。对比两组患者的血清炎症指标、应激反应、疼痛程度及并发症发生情况。结果术后,观察组的C反应蛋白、肿瘤坏死因子-α、白细胞介素-1β水平均低于对照组,组间差异有统计学意义(P<0.05)。术后,观察组的丙二醛水平低于对照组,超氧化物岐化酶、谷胱甘肽过氧化物酶水平均高于对照组,组间差异有统计学意义(P<0.05)。术后,观察组的疼痛视觉模拟评分为(1.02±0.15)分,低于对照组的(3.71±0.52)分,差异有统计学意义(P<0.05)。观察组的咀嚼无力、面部麻木发生率均高于对照组,组间差异有统计学意义(P<0.05)。两组的口唇疱疹、耳鸣发生率比较,组间差异无统计学意义(P>0.05)。结论经皮穿刺微球囊压迫术及微血管减压术治疗三叉神经痛各有优势,经皮穿刺微球囊压迫术能减轻患者术后炎症反应及应激反应,减轻疼痛,促进其身体恢复,微血管减压术后的并发症发生率低,临床应结合患者实际病情合理选择手术方案。
Objective To investigate the effect of percutaneous microballoon compression and microvascular decompression in the treatment of trigeminal neuralgia.Methods 84 patients with trigeminal neuralgia admitted to the Shanghe County People's Hospital from January 2022 to January 2023 were selected as the study objects and were divided into a control group and an observation group by random number table method,with 42 cases in each group.The control group underwent microvascular decompression and the observation group underwent percutaneous microballoon compression.The serum inflammatory indexes,stress responses,pain degree and complications were compared between the two groups.Results After operation,the levels of C-reactive protein,tumor necrosis factor-α and interleukin-1β in the observation group were lower than those in the control group,the differences between the groups were statistically significant(P<0.05).After operation,the level of malondialdehyde in the observation group was lower than that in the control group,and the levels of superoxide dismutase and glutathione peroxidase were higher than those in the control group,the differences between the groups were statistically significant(P<0.05).After surgery,the pain of Visual Analogue Scale score of the observation group was(1.02±0.15)points,lower than(3.71±0.52)points of the control group,and the difference was statistically significant(P<0.05).The incidences of masticatory weakness and facial numbness in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05);while there were no significant differences in the incidences of cold sores and tinnitus between the two groups(P>0.05).Conclusion Percutaneous microballoon compression and microvascular decompression have their respective advantages in the treatment of trigeminal neuralgia.Percutaneous microballoon compression can reduce postoperative inflammation and stress response,relieve pain and promote physical recovery,while the incidence of complications after microvascular decompression is low.The surgical plan should be reasonably selected according to the actual condition of patients.
作者
白清松
王立国
BAI Qingsong;WANG Liguo(Department of Neurosurgery,Shanghe County People's Hospital,Jinan Shandong,251600,China)
出处
《反射疗法与康复医学》
2023年第17期153-156,共4页
Reflexology And Rehabilitation Medicine
关键词
三叉神经痛
经皮穿刺微球囊压迫术
微血管减压术
血清炎症指标
并发症
Trigeminal neuralgia
Percutaneous microballoon compression surgery
Microvascular decompression surgery
Serum inflammatory indexes
Complications
作者简介
白清松(1986-),男,山东济南人,本科,主治医师,研究方向:三叉神经痛诊疗。
