摘要
目的分析胸腹腔镜食管癌根治术与开放食管癌根治术对食管癌对患者手术相关指标及免疫功能的影响。方法回顾性分析2019年3月—2020年3月于济宁市第三人民医院行手术治疗的70例食管癌患者的电子病例资料,根据手术方式不同分为开放组及胸腹腔镜组。开放组(n=32)行开放食管癌根治术,胸腹腔镜组(n=38)行胸腹腔镜食管癌根治术。比较两组患者的手术相关指标、免疫功能及术后并发症发生情况。结果胸腹腔镜组的术中出血量为(79.76±18.45)mL,少于开放组的(121.44±25.31)mL,手术时间为(288.59±38.19)min,长于开放组的(221.20±32.77)min,组间差异有统计学意义(P<0.05)。术后1、7 d,胸腹腔镜组的CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均高于开放组,CD8^(+)水平均低于开放组,组间差异有统计学意义(P<0.05)。两组的术后并发症发生率比较,差异无统计学意义(P>0.05)。结论胸腹腔镜食管癌根治术对机体的创伤更小,有利于改善食管癌患者的术后免疫功能,且并发症发生率较低,值得临床推广使用。
Objective To analyze the effects of thoracic laparoscopic radical resection and open radical resection on surgical related indicators and immune function of patients with esophageal cancer.Methods The electronic medical data of 70 patients with esophageal cancer who underwent surgical treatment in Jining Third People's Hospital from March 2019 to March 2020 were retrospectively analyzed,and they were divided into an open group and a thoracic laparoscopic group according to different surgical methods.The open group(n=32)underwent open radical resection,and the thoracic laparoscopic group(n=38)underwent thoracic laparoscopic radical resection.The surgical related indicators,immune function and postoperative complications were compared between the two groups.Results The intraoperative blood loss in the thoracic laparoscopic group was(79.76±18.45)mL,less than(121.44±25.31)mL in the open group,and the operative time was(288.59±38.19)min,longer than(221.20±32.77)min in the open group,the differences between the groups were statistically significant(P<0.05).On day 1 and 7 after surgery,the levels of CD3^(+),CD4^(+)and CD4^(+)/CD8^(+)in the thoracic laparoscopic group were higher than those in the open group,and the levels of CD8+were lower than those in the open group,the differences between the groups were statistically significant(P<0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusion Thoracic laparoscopic radical resection of esophageal cancer has less trauma to the body,is conducive to improving the postoperative immune function of esophageal cancer patients,and the incidence of complications is lower,which is worthy of clinical promotion.
作者
朱宁举
ZHU Ningju(Department of Thoracic Surgery,Jining Third People's Hospital,Jining Shandong,272100,China)
出处
《反射疗法与康复医学》
2023年第18期135-138,共4页
Reflexology And Rehabilitation Medicine
关键词
食管癌
胸腹腔镜食管癌根治术
开放食管癌根治术
免疫功能
Esophageal cancer
Thoracic laparoscopic radical resection of esophageal cancer
Open radical resection of esophageal cancer
Immune function
作者简介
朱宁举(1985-),男,山东济宁人,本科,主治医师,研究方向:胸外科肺及食管疾病诊疗。
