摘要
目的探究腹腔镜辅助胃癌根治术(LAG)与传统开腹术(TOS)对治疗Ⅱ期、Ⅲ期胃癌的近期及远期疗效.方法选取我院2018年1月—2020年2月收治的90例Ⅱ期、Ⅲ期胃癌患者为研究对象,按信封法将其分为对照组和观察组,每组45例,对照组采取TOS,观察组采取LAG.比较两组近期及远期疗效的差异.结果观察组手术时间、排气时间、住院时间均短于对照组,出血量少于对照组,组间差异有统计学意义(P<0.05).两组患者1年累计生存率对比,差异无统计学意义(P>0.05);观察组2年、3年累计生存率分别为85.00%、72.50%,均高于对照组的65.00%、47.50%,组间差异有统计学意义(P<0.05).术后,两组血清肿瘤标志物指标均较术前下降,且观察组低于对照组,差异有统计学意义(P<0.05).结论对Ⅱ期、Ⅲ期胃癌患者采取LAG效果显著,比TOS的疗效更好,能有效提高近期疗效和远期疗效,改善血清肿瘤标志物水平.
Objective Exploring the short-term and long-term efficacy of laparoscopic assisted radical gastrectomy(LAG)and traditional open surgery(TOS)in the treatment of stageⅡandⅢgastric cancer.Methods Selecting 90 patients with stageⅡandⅢgastric cancer admitted to our hospital from January 2018 to February 2020 as research objects.Divided into a control group and an observation group by envelope method,with 45 cases in each group,TOS operation was performed in the control group,and LAG operation was performed in the observation group.Compare the differences in short-term and long-term therapeutic effects between two groups.Results The operation time,exhaust time,and hospital stay of the observa-tion group were shorter than those of the control group,the blood loss in the observation group was less than that in the con-trol group the difference between groups were statistically significant(P<0.05).The 1-year cumulative survival rate of the two groups was compared,there was no statistically significant difference between groups(P>0.05);the 2-year and 3-year cumu-lative survival rates of the observation group were 85.00%,72.50%,respectively,which were higher than 65.00%,47.50%of the control group,the difference between groups were statistically significant(P<0.05).After operation,serum tumor markers in both groups decreased,and the observation group was lower than the control group,the difference between groups was sta-tistically significant(P<0.05).Conclusion LAG has a significant effect on patients with stageⅡandⅢgastric cancer,can effectively improve short-term and long-term curative effects,improving serum tumor marker levels.
作者
刘稳
LIU Wen(Department of General Surgery,Zibo Linzi District Maternal and Child Health Hospital,Zibo Shandong,255400,China)
出处
《反射疗法与康复医学》
2024年第2期185-187,共3页
Reflexology And Rehabilitation Medicine
关键词
腹腔镜辅助胃癌根治术
传统开腹术
Ⅱ期、Ⅲ期胃癌
近期疗效
远期疗效
Laparoscopic assisted radical gastrectomy for gastric cancer
Traditional open surgery
StageⅡandⅢgas-tric cancer
Short-term curative effects
Long-term curative effect
作者简介
刘稳(1975-),男,山东淄博人,本科,副主任医师,研究方向:普外科疾病诊治。