摘要
目的分析神经内镜微创术对老年高血压性脑出血(HICH)患者的影响.方法选取2022年5月—2023年5月该院收治的60例老年HICH患者为研究对象,按随机数字表法将其分为对照组与观察组,各30例.对照组行小骨窗开颅术,观察组行神经内镜微创术,术后两组均随访3个月.对比两组患者的手术情况、神经因子、炎性反应及并发症发生情况.结果观察组术中出血量为(68.96±5.31)mL,少于对照组的(131.43±7.46)mL,血肿清除率为93.33%,高于对照组的73.33%,手术时间为(65.34±5.29)min,住院时间为(12.46±2.57)d,均短于对照组的(106.82±8.31)min、(18.63±3.49)d,并发症发生率为3.33%,低于对照组的26.67%,组间差异有统计学意义(P<0.05).术后1周,观察组神经元特异性烯醇化酶为(6.89±1.02)μg/L,S-100β蛋白为(0.13±0.01)ng/mL,P物质为(265.37±15.31)ng/L,C反应蛋白为(8.63±1.12)mg/L,白细胞介素-6为(28.49±2.68)ng/L,肿瘤坏死因子-α为(31.24±4.77)μg/L,均低于对照组的(10.53±1.56)μg/L、(0.36±0.05)ng/mL、(336.54±18.69)ng/L、(11.24±1.59)mg/L、(35.21±3.57)ng/L、(47.53±6.25)μg/L,组间差异有统计学意义(P<0.05).结论神经内镜微创术具有创伤小、血肿清除率高等优势,能够减轻神经功能损伤,控制炎性反应,且并发症少.
Objective To analyze the effect of minimally invasive neuroendoscopy surgery on elderly patients with hypertensive intracerebral hemorrhage(HICH).Methods 60 elderly patients with HICH treated in our hospital from May 2022 to May 2023 were selected as the study objects,and were divided a control group and an observation group according to random number table method,with 30 cases in each group.The control group underwent small bone window craniotomy,and the observation group underwent minimally invasive neuroendoscopy surgery.Both groups were followed up for 3 months.The operation status,neurofactors,inflammatory response and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was(68.96±5.31)mL,less than(131.43±7.46)mL in the control group,the clearance rate of hematoma was 93.33%,higher than 73.33%in the control group,the operation time was(65.34±5.29)min,and the length of hospitalization was(12.46±2.57)d,were shorter than(106.82±8.31)min and(18.63±3.49)d in the control group,and the incidence of complications was 3.33%,lower than 26.67%in the control group,with statistical significance(P<0.05).One week after operation,neuron-specific enolase,S-100βprotein,substance P,C-reactive protein,Interleukin-6 and tumor necrosis factor-αin the observation group were(6.89±1.02)g/L,(0.13±0.01)ng/mL,(265.37±15.31)ng/L,(8.63±1.12)mg/L,(28.49±2.68)ng/L,(31.24±4.77)g/L,respectively,which were lower than(10.53±1.56)g/L,(0.36±0.05)ng/mL,(336.54±18.69)ng/L,(11.24±1.59)mg/L,(35.21±3.57)ng/L,(47.53±6.25)g/L of the control group,the differences between groups were statistically significant(P<0.05).Conclusion Minimally invasive neuroendoscopy surgery has the advantages of small trauma and high hematoma clearance,which can reduce neurological damage,control inflammatory reaction,and has fewer complications.
作者
张雷
ZHANG Lei(Department of Neurosurgery,Caoxian People's Hospital,Heze Shandong,274400,China)
出处
《反射疗法与康复医学》
2024年第6期123-125,129,共4页
Reflexology And Rehabilitation Medicine
关键词
老年高血压性脑出血
神经内镜微创术
炎性反应
并发症
Hypertensive intracerebral hemorrhage in the elderly
Minimally invasive neuroendoscopy surgery
Inflammatory reaction
Complications
作者简介
张雷(1992-),男,山东菏泽人,本科,主治医师,研究方向:神经外科疾病诊疗。
