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硬膜外应用舒芬太尼复合罗哌卡因对开胸手术后镇痛的临床研究

Clinical Study of Epidural Sufentanil Combined with Ropivacaine for Alleviating Pain after Thoracotomy
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摘要 目的:探讨硬膜外应用舒芬太尼复合罗哌卡因对开胸手术后镇痛的临床影响.方法:选取本院2016年1月至2019年1月择期进行开胸手术的患者120例,根据随机数表法将患者分为对照组(n=58)和观察组(n=62).对照组患者只使用舒芬太尼进行术后镇痛,观察组患者用舒芬太尼复合罗哌卡因进行术后镇痛.比较两组患者镇痛效果、血压、心率及不良反应.结果:两组患者在术后24h内视觉模拟评分法(VAS)疼痛评分先上升后下降,在各个不同时点上,观察组VAS评分明显低于对照组(P<0.05);观察组患者舒张压(DBP)、收缩压(SBP)、心率(HR)以及脉搏血氧饱和度(SpO2)水平明显低于对照组患者(P<0.05);观察组患者不良反应率为19.35%,对照组患者不良反应率为29.30%,差异较小(P>0.05),观察组患者发生恶心呕吐明显少于对照组患者,发生低血压明显高于对照组患者(P<0.05);观察组患者满意度为93.54%(58/62),对照组患者满意度为74.14%(43/58),观察组患者满意度明显高于对照组患者(P<0.05).结论:舒芬太尼复合罗哌卡因用于全身麻醉开胸患者硬膜外术后镇痛,其镇痛效果显著,患者心血管系统平稳,使用后不良反应较少,患者满意度较高,临床效果明显. Objective:To investigate the clinical effect of epidural sufentanil combined with ropivacaine on thoracotomy.Methods:A total of 120 patients undergoing thoracotomy in our hospital from January 2016 to January 2019 were selected,and the patients were divided into a control group(n=58)and an observation group(n=62)according to the random number table method.Patients in the control group used sufentanil alone for postoperative analgesia,and patients in the observation group used sufentanil combined with ropivacaine for postoperative analgesia.The analgesic effect,blood pressure,heart rate and adverse reactions of the two groups were compared.Results:The visual analogue scale(VAS)scores of the two groups of patients rose first and then fell within 24 hours after surgery.At different time points,the VAS scores of the observation group were significantly lower than those of the control group(P<0.05);the levels of DBP,SBP,HR and SpO2 in the observation group were significantly lower than those of the control group(P<0.05);the adverse reaction rate of the observation group was 19.35%,and the adverse reaction rate of the control group was 29.30%,with a small difference between(P>0.05).The observation group had signifcantly less nausea and vomiting.In the control group,hypotension was significantly higher than that in the control group(P<0.05);the observation group's patient satisfaction rate was 93.54%(58/62),and the control group's patient satisfaction rate was 74.14%(43/58),with sigificantly higher rate of the observation group than that of the control group(P<0.05).Conclusion:Compared with application alone,sufentanil combined with ropivacaine has more obvious analgesic effect after thoracotomy,with patients showing more stable cardiovascular system,fewer adverse reactions and higher satisfaction after use.
作者 陈桃丽 CHEN Tao-li(Department of Anesthesiology,Xinmi City Traditional Chinese Medicine Hospital,Zhengzhou 452370,China)
出处 《四川解剖学杂志》 2021年第4期40-43,共4页 Sichuan Journal of Anatomy
关键词 硬膜外 舒芬太尼 罗哌卡因 开胸手术 术后镇痛 Epidural Sufentanil Ropivacaine Thoracotomy Postoperative analgesia
作者简介 陈桃丽,主治医师,本科学历,研究方向:普外科麻醉,e-Mail:qae7ww@163.com
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