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眼部移植物抗宿主病(GVHD)1例

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摘要 患者女,10岁.以“右眼红、异物感、畏光反复发作半年”为主诉就诊.该患儿近半年反复发生右眼红、异物感、畏光症状,曾多次于我院就诊,曾诊断为“右眼角膜炎”给予更昔洛韦凝胶、左氧氟沙星眼液、小牛血去蛋白凝胶等眼部局部用药治疗,症状未见好转.近1周上述症状较前加重,于我院复诊.查体:双眼睑缘充血,睑板腺开口萎缩,睑结膜充血,睑结膜血管模糊,见乳头增生,右眼角膜中下方上皮片状浸润,左眼角膜光泽.辅助检查:眼压:右眼15mmHg,左眼14 mmHg;泪液分析:泪膜破裂时间(BUT):右眼2 s,左眼3 s;角膜荧光染色(FL)右眼3分,左眼1分.详细询问病史:患儿有鸡蛋、牛奶过敏史.1年前患儿因“再生障碍性贫血”曾行造血干细胞移植术.确定诊断:眼部移植物抗宿主病(graftversus host disease,GVHD).治疗:妥布霉素地塞米松眼膏日3次涂双眼,羟糖苷眼水日3次点双眼.1周后患儿复查,症状明显好转.
作者 董翠翠 杨序
机构地区 抚顺市眼病医院
出处 《中国实用眼科杂志》 2018年第1期85-85,共1页 Chinese Journal of Practical Ophthalmology
作者简介 通信作者:董翠翠,Email:dongcuicui19840225@163.com
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