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不同渗透压对比剂对心率的影响

Comparison of the Effect of Contrast Agents with Different Osmolar on Heart Rate
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摘要 目的 探讨冠脉CT血管成像(computed tomography angiography,CTA)中不同渗透压对比剂对患者心率的影响.方法 回顾性分析89例行冠脉CTA检查患者的临床资料,分为碘海醇组(n=42)、碘克沙醇组(n=47).记录两组注射对比剂前5 min和注射后最高心率,计算患者心率变化量.比较两种对比剂对患者心率的影响.结果 所有患者均顺利完成冠脉CTA检查.两组患者注射对比剂后心率均显著升高(P<0.05),两组间差异无统计学意义(P=0.461).长期服用β受体阻滞剂的患者的心率变化量显著低于未服用者(P<0.05).结论 碘海醇与碘克沙醇均可导致心率显著升高,两组间无差异,服用β受体阻滞剂可减小对比剂对心率的影响. Objective To investigate the effect of contrast agents with different osmolar on heart rate(HR)during coronary CT angiography(CTA).Methods The clinical data of 89 patients who had underwent coronary CTA were retrospectively analyzed.The patients were divided into Iohexol group(n=42)and Iodixanol group(n=47).The HR at 5 min before contrast agent injection and the maximum HR after injection were recorded,and the change of HR were calculated.The pre-contrast HR,maximum post-contrast HR and HR change were compared between the two groups.Results All patients successfully underwent the coronary CTA.HR were significantly increased in both the two groups(P<0.05),no significant differences were observed between the two groups(P=0.461).The HR change of patient on long-termβ-blockers were significantly lower than those who were not on long-termβ-blockers(P<0.05).Conclusion Both Iohexol and Iodixanol could significantly increase patients'HR with no significant difference between the two groups.β-blockers might be helpful in reducing the effect of contrast agents on HR.
作者 王洁 吴敏 WANG Jie;WU Min(Department of Radiology,the First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,215006,China)
出处 《中国血液流变学杂志》 CAS 2020年第3期392-394,405,共4页 Chinese Journal of Hemorheology
关键词 对比剂 肺栓塞 螺旋CT 心率 contrast agent pulmonary embolism spiral computed tomography heart rate
作者简介 王洁(1992-),女,江苏苏州人,学士,技师,从事放射技术工作。
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