摘要
肥厚型心肌病(HCM)是一种常见的遗传性心肌病,估算我国成人HCM患者超过100万。少数HCM患者病情进展,出现严重的收缩功能障碍,即终末期肥厚型心肌病(end-stage phase of HCM,ES-HCM)。ES-HCM病情危重、并发症多、治疗效果欠佳,严重威胁患者生命健康,已受到国内外学者的广泛关注。本文将对ES-HCM的流行病学、发病机制、诊断、治疗等内容进行综述。
Hypertrophic cardiomyopathy (HCM), a common hereditary cardiomyopathy, threatens approximately 1 million individuals in China. Some patients with HCM may progress to an end-stage phase of HCM (ES-HCM) with severe systolic dysfunction. Characterized by the serious complications, and poor treatment effect, ES-HCM has been widely concerned by researches worldwide. Herein, we review recent advances in ES-HCM from epidemiology, pathogenesis, diagnosis, and treatment strategies.
作者
戴雅青
谢文辉
洪华山
Dai Yaqing;Xie Wenhui;Hong Huashan(Union Clinical Medical College of Fujian Medical University,Fuzhou 350001,China;Department of Geriatrics of Fujian Medical University Union Hospital,Fujian Provincial Key Laboratory of Vascular Aging,Fujian Institutes of Geriatrics,Fujian Heart Medical Center,Fuzhou 350001,China)
基金
国家临床重点专科建设项目(2013544)
福建省临床重点专科建设项目(2012149)
关键词
心肌病
肥厚型
终末期
诊断
治疗
Cardiomyopathy,hypertrophic
End-stage
Diagnosis
Treatment Contributor Information
作者简介
通信作者:洪华山,Email:15959159898@163.com
