摘要
Based on the energy conversion of light into sound,photoacoustic computed tomography(PACT)is an emerging biomedical imaging modality and has unique applications in a range of biomedical fields.In PACT,image formation relies on a process called acoustic inversion from received photoacoustic signals.While most PACT systems perform this inversion with a basic assumption that biological tissues are acoustically homogeneous,the community gradually rea-lizes that the intrinsic acoustic heterogeneity of tissues could pose distortions and artifacts to finally formed images.This paper surveys the most recent research progress on acoustic het-erogeneity correction in PACT.Four major strategies are reviewed in detail,including half-time or partial-time reconstruction,autofocus reconstruction by optimizing sound speed maps,joint reconstruction of optical absorption and sound speed maps,and ultrasound computed tomog-raphy(USCT)enhanced reconstruction.The correction of acoustic heterogeneity helps improve the imaging performance of PACT.
基金
supported in part by the National Natural Science Foundation of China(NSFC)under Grant No.61705216
in part by the Major Science and Technology Project of Anhui Province under Grant No.18030801138
in part by the Zhe-jiang Lab under Grant No.2019MC0AB01
in part by the Research Funds of the Double First-Class Initiative
in part by the Research Fund of the USTC Smart City Institute
in part by the CAS Pioneer Hundred Talents Program
in part by the Startup Fund of the University of Science and Technology of China(USTC)
作者简介
Corresponding author:Chao Tian,ctian@ustc.edu.cn