摘要
目的:探讨超声剪切波弹性成像联合血清趋化因子配体8(CXCL8)在直肠癌诊断及TNM分期中的应用价值。方法:回顾性分析2020-2022年我院收治的100例直肠癌患者临床资料,将其纳入观察组;另选同期体检健康者100名,将其纳入对照组。采用超声剪切波弹性成像技术检查,并检测血清CXCL8水平。结果:观察组患者肿瘤病灶、周围脂肪、正常直肠壁杨氏模量值均高于对照组(P<0.05),Ⅲ~Ⅳ期肿瘤病灶、周围脂肪、正常直肠壁杨氏模量值均高于Ⅰ~Ⅱ期(P<0.05),观察组患者血清CXCL8水平明显高于对照组(P<0.05),Ⅲ~Ⅳ期患者血清CXCL8水平明显高于Ⅰ~Ⅱ期(P<0.05)。超声剪切波弹性成像联合血清CXCL8诊断TNM分期价值最高。结论:超声剪切波弹性成像联合血清CXCL8可提高直肠癌TNM分期诊断准确率,建议使用。
Objective To evaluate the application value of ultrasonic shearing wave elastic imaging(USSWEI)combined with detecting serum CXCL8 in diagnosing rectal cancer and TNM staging.Methods Retrospectively reviewed the clinical data of 100rectal cancer patients treated in author’s hospital(2020-2022)who were taken as observation group,at the same time 100 persons who received physical exam.as control group;both groups were inspected with USSWEI,and detected with CXCL8 level.Results In tumor lesion,peripheral fat,Yang’s model value of normal rectal wall observation group was all higher than control group(P<0.05);the above-mentioned three parameterⅢ-Ⅳstage were higher than that ofⅠ-Ⅱstage(P<0.05).The level of serum CXCL8 in the patients of observation group was significantly higher than control group(P<0.05),meanwhile,the level atⅢ-Ⅳstage was significantly than one atⅠ-Ⅱstage(P<0.05).When USSWEI combined with detecting serum CXCL8 level,the diagnostic value for TNM staging was most high.Conclusion USSWEI combined with detecting serum CXCL8 level can enhance the accurate rate in staging diagnosing TNM stage of rectal cancer.
作者
王刚
WANG Gang(Tongxu County's Hospital of TCM,Kaifeng,Henan 475400)
出处
《中国肛肠病杂志》
2022年第10期14-16,共3页
Chinese Journal of Coloproctology
作者简介
第一作者:王刚,男,河南通许人,主治医师,研究方向:超声波医学。E-mail:814809375@qq.com
