摘要
目的:探讨不同术式对结直肠癌急性肠梗阻患者炎症因子、应激反应及术后尿潴留的影响。方法:将68例结直肠癌急性肠梗阻患者随机分为观察组和对照组,每组34例。观察组患者采用腹腔镜手术治疗,对照组患者采用开腹手术治疗,比较2组患者手术前后炎症因子、C反应蛋白、应激指标及术后尿潴留发生情况。结果:术前2组患者白细胞介素1(IL-1)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)水平比较差异无统计学意义(P>0.05);术后观察组患者IL-1、TNF-α、CRP水平均低于对照组(P<0.05)。术前2组患者丙二醇(MDA)、超氧化物歧化酶(SOD)水平比较差异无统计学意义(P>0.05);术后观察组患者MDA水平低于对照组(P<0.05),SOD水平高于对照组(P<0.05)。2组患者术后尿潴留发生率比较差异无统计学意义(P>0.05)。结论:结直肠癌急性肠梗阻患者行腹腔镜手术,不仅能够改善患者的炎症反应和应激反应,而且对术后尿潴留的不良影响小。
Objective To investigate the impact of different procedures on acute intestinal obstruction(AIO),inflammatory factors,stress response,and postoperative uroschesis of colorectal cancer patients.Methods Randomly divided 68 patients with colorectal cancer complicated AIO treated in author’s hospital into observation group(34 cases,received laparoscopic surgery)and control group(34 cases,instead of open one);then,compared inflammatory factors,CRP and stress norms before and after surgery,as well as postoperative uroschesis status.Results Before surgery,in the levels of IL-1,TNF-α,and CRP there was no statistical difference between the two groups(P>0.05),but after surgery the levels of above factors in observation group were all lower than that in control group(P<0.05);before surgery the levels of MDA and SOD of both groups had no statistical difference(P>0.05),but after surgery,in the MDA level,the SOD level observation group was respectively lower,higher than control group(P<0.05);in the postoperative incidence of uroschesis there was no statistical difference between the two groups(P>0.05).Conclusion Compared with open one,laparoscopic surgery for colorectal cancer complicated with AIO not only can improve patients’inflammatory reaction and stress response,but less adversely impacting postoperative uroschesis.
作者
李冰鹤
LI Bing-he(Division of Emergency Medicine,the First Affiliated Hospital of Henan Sci-tech University,Luoyang,Henan 471000)
出处
《中国肛肠病杂志》
2022年第10期21-23,共3页
Chinese Journal of Coloproctology
关键词
结直肠癌
急性肠梗阻
手术
炎症因子
应激反应
尿潴留
Colorectal cancer
Acute intestinal obstruction
Surgery
Inflammatory factor
Stress response
Uroschesis
作者简介
第一作者:李冰鹤,女,河南洛阳人,住院医师,研究方向:急诊肛肠相关。E-mail:1298830862@qq.com
