摘要
目的探讨血清可溶性白细胞分化抗原14亚型(Presepsin)、降钙素原(PCT)检测在成人败血症早期诊断中的价值。方法选取2018年11月~2019年10月在佳木斯大学附属第一医院感染科住院治疗的100例怀疑败血症的患者为实验组,根据血培养结果将其分为败血症组(35例)、一般细菌感染组(46例)、病毒及其他感染组(19例),另选取同期我院体检健康者30例为对照组。所有对象均于入院当天应用抗菌药物治疗前采血,检测血常规、Presepsin、降钙素原(PCT),同时完善血培养检查。结果败血症组外周血中presepsin、PCT水平均高于一般细菌感染组、病毒及其他感染组和对照组,且一般细菌感染组高于病毒及其他感染组和对照组,差异均有统计学意义(P<0.05),病毒及其他感染组与对照组外周血中presepsin、PCT、WBC水平比较(P>0.05);一般细菌感染组、病毒及其他感染组和对照组中外周血中WBC水平比较(P>0.05)。结论presepsin及PCT的升高程度可反映细菌感染的的严重程度,在败血症的早期诊断中具有重要意义。
Objective To investigate the value of serum soluble cluster of differentiation 14 subtype(Presepsin)and procalcitonin(PCT)in early diagnosis of adult septicemia.Methods 100 patients suspected of septicemia who were hospitalized in the department of infection of Jiamusi university affiliated first hospital from November 2018 to October 2019 were selected as clinical observation objects.according to the blood culture results,they were divided into septicemia group(35 cases),general bacterial infection group(46 cases),virus and other infection group(19 cases),and control group(30 healthy people)at the same period.All the patients in each group took blood on the day of admission before treatment with antibacterial drugs.Blood routine test,Presepsin and procalcitonin(PCT)results were detected.Meanwhile,blood culture test was improved.Results The contents of presepsin and PCT in peripheral blood of patients with septicemia were higher than that of normal bacterial infection group,virus and other infection group and control group,and the normal bacterial infection group was higher than that of virus and other infection group and control group,while the values of the two groups were similar between virus and other infection group and control group.The white blood cell content in the peripheral blood of patients with septicemia is higher than that of normal bacterial infection group,virus and other infection group and control group,but the values in normal bacterial infection group,virus and other infection group and control group are similar.Conclusion The elevated levels of presepsin and PCT can reflect the severity of bacterial infection,which is of great significance in the early diagnosis of septicemia.
作者
侯平
王国涛
代立娟
Hou Ping;Wang Guotao;Dai Lijuan(The First Affiliated Hospital of Jiamusi University,Jiamusi 154000,China)
出处
《广东化工》
CAS
2020年第3期80-81,共2页
Guangdong Chemical Industry
作者简介
侯平(1993-),女,黑龙江人,硕士研究生,主要研究方向为感染性疾病;通讯作者:代立娟
