摘要
目的比较腹腔镜下胰十二指肠切除术(laparoscopicpancreatoduodenectomy,LPD)与传统开放手术在围术期安全以及有效性的不同。方法收集2018年8月至2021年2月在安徽医科大学第一附属医院肝胆胰外科接受胰十二指肠切除术治疗的54例病例的临床病理资料,其中腹腔镜手术以及开放手术各27例,比较两组患者之间的围术期情况,术后并发症、术后病理资料等。结果LPD组患者的手术时间明显长于OPD(open pancreaticoduodenectomy,OPD)组[(6.547±1.389)h vs(5.010±1.073)h,t=4.552,P<0.001],而这两组在术中出血量、术后排便时间、术后进食时间、术后住院时间方面无统计学差异(P>0.05)。而两组患者在术后并发症发生情况方面也没有明显差异(P>0.05)。两组的术后肿瘤病理中,肿瘤类型、肿瘤直径、清扫的总淋巴结数、切缘情况之间无统计学意义(P>0.05)。结论LPD手术方式相较于传统的开放手术,其安全性及有效性相当,有较好的发展前景。
Objective To compare different methods of laparoscopic pancreatoduodenectomy(LPD)with conventional open surgery in terms of perioperative safety as well as efficacy.Methods Clinicopathological data were collected from 54 patients who underwent pancreatoduodenectomy between August 2018 and February 2021 at the Department of hepatobiliary and pancreatic surgery of the First Affiliated Hospital of Anhui Medical University.Among them,laparoscopic surgery as well as open surgery were performed in 27 patients each,and the perioperative conditions,postoperative complications,postoperative pathological data,etc.were compared between the two groups.Results The LPD group had a significantly longer operative time than the OPD(open pancreaticoduodenectomy,OPD)Group[(6.547±1.389)h vs(5.010±1.073)h,t=4.552,P<0.001],whereas these two groups did not differ statistically in terms of intraoperative blood loss,postoperative defecation time,postoperative feeding time,and postoperative hospital stay(P>0.05).However,there were also no significant differences in the occurrence of postoperative complications between the two groups(P>0.05).There were no statistically significant differences in postoperative tumor pathology between the two groups regarding tumor type,tumor diameter,number of total lymph nodes dissected,and margin status(P>0.05).Conclusion LPD surgical approach has a relatively good safety and efficacy profile compared with conventional open surgery.
作者
左孝民
孟翔凌
陈伟
ZUO Xiao⁃min;MENG Xiang⁃ling;CHEN Wei(the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)
出处
《肝胆外科杂志》
2022年第4期258-261,共4页
Journal of Hepatobiliary Surgery
