摘要
目的:研究乳腺癌前哨淋巴结转移的相关因素,为临床判断病情、制定治疗方案提供依据。方法:选取2016年6月至2018年6月我院乳腺癌患者200例作为研究对象,其中前哨淋巴结转移者112例,前哨淋巴结未转移者88例,分析乳腺癌前哨淋巴结转移的相关因素。结果:年龄、BMI、绝经情况、分子分型与乳腺癌前哨淋巴结转移无明显相关性(P>0.05);原发肿瘤位置、病理分型、组织学分级、脉管是否浸润、肿瘤大小是乳腺癌前哨淋巴结转移的影响因素(P<0.05);经多因素Logistic回归分析可知,脉管浸润、肿瘤>2 cm、组织学分级是乳腺癌前哨淋巴结转移的独立危险因素(P<0.05)。结论:脉管浸润、肿瘤≥2 cm、组织学分级是乳腺癌前哨淋巴结转移的独立危险因素,临床应及早明确上述情况,为临床准确判断病情、制定治疗方案提供可靠信息支持。
Objective:To determine the related factors of sentinel lymph node metastasis in breast cancer,and to provide evidence for clinical judgment and treatment protocol.Methods:A total of 200 patients with breast cancer admitted to our hospital between June 2016 and June 2018 were included as the subjects in the study.Among them,there were 112 of sentinel lymph node metastasis and 88 of non-sentinel lymph node metastasis.The factors related to sentinel lymph node metastasis were analyzed.Results:There were no significant correlation between age,body mass index(BMI),menopausal status,molecular typing and sentinel lymph node metastasis(P>0.05).Primary tumor location,pathological type,histological grade,vascular infiltration,tumor size were the influencing factors of sentinel lymph node metastasis in breast cancer(P<0.05).Multivariate logistic regression analysis showed that vascular invasion,tumor>2 cm,and histological grade were independent risk factors for sentinel lymph node metastasis in breast cancer(P<0.05).Conclusion:Vascular invasion,tumor≥2 cm,and histological grade are independent risk factors for sentinel lymph node metastasis in breast cancer.The clinical situation should be clearly identified as early as possible to provide reliable information supportive of accurate diagnosis and treatment protocol development in clinical settings.
作者
邓丁梅
王永霞
张玉娟
叶建森
Deng Dingmei;Wang Yongxia;Zhang Yujuan;Ye Jiansen(Department of Breast,Dongguan Municipal People's Hospital,Dongguan,Guangdong 523000,China)
出处
《广州医科大学学报》
2019年第3期48-50,共3页
Academic Journal of Guangzhou Medical University
基金
广东省医学科学技术研究基金项目(A2018195).
关键词
乳腺癌
前哨淋巴结转移
相关因素
Breast cancer
sentinel lymph node metastasis
related factors
作者简介
通讯作者:邓丁梅,Email:dengdingmei@163.com
