摘要
目的对七氟烷的逐渐增量诱导法与高浓度快速诱导法在老年肿瘤患者手术中的应用效果进行比较。方法选择2021年1—12月永昌县人民医院收治的老年肿瘤患者80例,随机分为逐渐增量组和快速诱导组各40例。逐渐增量组氟烷吸入浓度初始为1%,后逐渐增加至5%;快速诱导组七氟烷吸入浓度始终维持在5%,其余麻醉方法和手术常规进行。比较两组患者麻醉后的血流动力学参数、术后恢复和免疫功能。结果两组患者插管即刻和插管后平均动脉压差异有统计学意义(P<0.05)。两组患者诱导时间、插管时间、苏醒时间差异有统计学意义(P<0.05)。两组患者术后1 d CD4差异有统计学意义(P<0.05)。结论七氟烷逐渐增量诱导法应用于老年肿瘤患者手术,血压稳定性较好,术后苏醒时间短,而且有利于早期免疫功能恢复,值得临床推广应用。
Objective To compare the application effect of sevoflurane gradual incremental induction method and high concentration rapid induction method in elderly tumor patients.Methods A total of 80 elderly tumor patients admitted to Yongchang County People’s Hospital from January to December 2021 were randomly divided into gradual increment group and rapid induction group with 40 cases each.The inhalation concentration of halothane in the incremental group was 1%at the beginning,and then gradually increased to 5%.The inhalation concentration of sevoflurane in the rapid induction group was maintained at 5%all the time.The other anesthesia methods and operations were performed routinely.The hemodynamic parameters,postoperative recovery and immune function were compared between the two groups.Results There was significant difference in mean arterial pressure between the two groups at the time of intubation and after intubation(P<0.05).There were significant differences in induction time,intubation time and awakening time between the two groups(P<0.05).There was significant difference in CD4level at 1 day after operation between the two groups(P<0.05).Conclusion Sevoflurane gradual incremental induction method could keep blood pressure stability,short postoperative recovery time,and recovery immune function in surgical treatment of for elderly tumor patientswhich is worthy of clinical application.
作者
杨永智
YANG Yongzhi(Department of Anesthesiology,Yongchang County People's Hospital,Jinchang 737299,Gansu Province,China)
出处
《中国实用乡村医生杂志》
2022年第12期66-68,72,共4页
Chinese Practical Journal of Rural Doctor
关键词
七氟烷
肿瘤
麻醉
诱导
老年
手术
Sevoflurane
Tumor
Anesthesia
Induction
Old age
Operation