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烯丙雌醇联合盐酸利托君治疗晚期习惯性流产的效果与安全性分析

Efficacy and Safety of Allylestrenol Combined with Ritodrine Hydrochloride in Patients with Late Habitual Abortion
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摘要 目的观察烯丙雌醇联合盐酸利托君治疗晚期习惯性流产(recurrent spontaneous abortion,RSA)的疗效与安全性。方法选取揭阳市慈云医院产科收治的晚期RSA患者150例,随机分为对照组和联合组各75例。对照组单用烯丙雌醇进行治疗,联合组在此基础上联用盐酸利托君,比较两组临床效果和不良反应发生情况。结果联合组治疗综合有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论烯丙雌醇对于晚期RSA具有一定的治疗效果,与盐酸利托君联合应用疗效更佳,且具有较高的用药安全性,值得临床推广使用。 Objective To observe the efficacy and safety of allylestrenol combined with ritodrine hydrochloride in the treatment of late recurrent spontaneous abortion(RSA).Methods A total of 150 patients with advanced RSA in Department of Obstetrics,Ciyun Hospital,Jieyang City were randomly divided into combination group and control group,75 cases in each group.The control group was treated with allylestrenol alone,and the combined group was treated with ritodrine hydrochloride on this basis.The clinical effects of the two groups were evaluated,and the incidence of adverse reactions was recorded.Results The comprehensive effective rate of combined group was significantly higher than that of control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Allylestrenol has a certain therapeutic effect on advanced RSA,and the combination of allylestrenol and ritodrine hydrochloride is more effective,and has higher safety,which is worthy of clinical application.
作者 江丽瑜 吴瑞芬 JIANG Liyu;WU Ruifen(Department of Obstetrics,Ciyun Hospital of Jieyang,Jieyang 522000,Guangdong Province,China)
出处 《中国实用乡村医生杂志》 2023年第2期36-38,共3页 Chinese Practical Journal of Rural Doctor
关键词 烯丙雌醇 盐酸利托君 晚期习惯性流产 疗效 安全性 Allylestrenol Ritodrine Hydrochloride Late Recurrent Spontaneous Abortion Curative Effect Security
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