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卡贝缩宫素与缩宫素治疗奶牛产后胎衣不下的比较研究 被引量:1

Comparative study on the effect of carbetocin and oxytocin in the treatment of retention of placenta in dairy cows
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摘要 为评估卡贝缩宫素对治疗初产奶牛产后胎衣不下的作用,试验将妊娠期满、即将分娩的头胎奶牛190头随机分为4组,分别为低剂量卡贝缩宫素组(210μg/头)、高剂量卡贝缩宫素组(350μg/头)、缩宫素对照组(200 IU/头)、空白对照组(生理盐水10 m L/头),观测对奶牛胎衣不下的治疗效果。结果表明:各组间奶牛胎衣不下发生率和胎衣排出时间差异不显著(P>0.05);低、高剂量卡贝缩宫素组的排乳率极显著高于缩宫素对照组和空白对照组(P<0.01),各组间排乳时间差异不显著(P>0.05);空白对照组子宫炎发生率显著高于高剂量卡贝缩宫素组(P<0.05),其他组间差异不显著(P>0.05)。采用双同期发情-定时输精程序,低、高剂量卡贝缩宫素组及缩宫素对照组、空白对照组间首配受胎率及首次配种间隔各组间差异不显著(P>0.05)。说明卡贝缩宫素对产后奶牛初乳的排出有显著促进作用,效果好于缩宫素;卡贝缩宫素预防奶牛胎衣不下的效果与缩宫素无差异,预防子宫炎的效果好于缩宫素,可用于初产奶牛产后护理。 In order to evaluate the effect of carbetocin on the treatment of retained placenta to the fresh cows at postpartum,190 cows that were at the end of the pregnancy and about to deliver were randomly divided into 4 groups,which were low-dose carbetocin groups(210μg per cow),high-dose carbetocin group(350μg per cow),oxytocin control group(200 IU per cow)and blank control group(normal saline 10 m L per cow),and the effect of treatment on retained placenta was observed among the groups.The results showed that:there was no significant difference in the rate of retained placenta and expulsion time of placenta among the groups(P>0.05).The rate of milk discharge was significantly higher in low-dose and high-dose carbetocin group than that of oxytocin control and blank control group(P<0.01),and there was no significant difference in the time of milk discharge among the groups(P>0.05).The incidence of metritis in the blank control group was significantly higher than that in the high-dose carbetocin group(P<0.05),but there was no significant difference between other groups.Using double estrus synchronization-timed artificial insemination(TAI)protocol,the conception rate of the first TAI at postpartum and the interval from calving to the first breeding were no significant different among the groups(P>0.05).In conclusion,carbetocin significantly promoted the discharge of colostrum at postpartum cows,and its effect of prevention to retaied placenta is better than that of oxytocin.There was no difference in the effect of the prevention and treatment to metritis between carbetocin and oxytocin.Therefore,carbetocin can be used for postpartum care of fresh cows.
作者 冯春涛 刘玉 赵永会 李欣 赵立平 李树静 FENG Chuntao;LIU Yu;ZHAO Yonghui;LI Xin;ZHAO Liping;LI Shujing(Shijiazhuang Tianquan Elite Dairy Co.Ltd.,Shijiazhuang 050200,China;Hebei Provincial Dairy Cow Breeding Engineering Technology Research Center,Shijiazhuang 050200,China;Animal Health Supervision Institute of Luquan District of Shijiazhuang,Shijiazhuang 050200,China;Hebei Cattle Industry Technology Research Institute,Shijiazhuang 050200,China;Animal Disease Prevention and Control Center of Luquan District of Shijiazhuang,Shijiazhuang 050200,China)
出处 《黑龙江动物繁殖》 2020年第4期7-10,14,共5页 Heilongjiang journal of animal reproduction
基金 “十三五”国家重点研发计划项目(2017FYD0501905) 河北省重点研发计划项目(18226615D,19226608D)
关键词 奶牛 卡贝缩宫素 缩宫素 胎衣不下 子宫炎 cows carbetocin oxytocin retained of placenta metritis
作者简介 冯春涛(1982—),男,高级畜牧师,硕士,主要从事胚胎生物技术研发和推广,fengchuntao@163.com;通信作者:李树静(1964—),男,研究员,博士,主要从事胚胎生物技术研发和推广,embryochina@163.com
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