摘要
目的:探讨接受抗病毒治疗的慢性乙型病毒性肝炎(慢性乙肝)患者采用连续性护理管理对提高其治疗依从性以及改善其预后所产生的影响。方法:随机选取慢性乙肝患者88例,自2022年1月~2022年10月在本院接受抗病毒治疗,以随机数字表法作为分组工具,随机将患者分成对照组(n=44)与观察组(n=44)。给予全部患者常规抗病毒治疗,对照组治疗期间以常规护理作为干预手段,观察组治疗期间以连续性护理管理作为干预手段,比较两组患者抗病毒治疗依从性、治疗前后肝纤维化指标、肝功能指标、药物不良反应发生率、再住院率及乙肝病毒脱氧核糖核酸(HBV DNA)转阴率。结果:观察组患者抗病毒治疗总依从性明显较对照组高(P<0.05)。干预前两组患者肝纤维化指标及肝功能指标水平无显著差异(P>0.05),干预后观察组患者各项指标水平均较对照组低(P<0.05)。两组患者药物不良反应发生率差异无统计学意义(P>0.05),观察组患者再住院率明显低于对照组(P<0.05)。观察组患者HBV DNA转阴率显著高于对照组(P<0.05)。结论:为采用抗病毒治疗的慢性乙肝患者提供连续性护理管理可使患者的抗病毒治疗依从性得到显著提高,可促进其肝功能改善,有效降低患者再住院率。
Objective:To investigate the effect of continuous nursing management on treatment compliance and prognosis of patients with chronic hepatitis B(CHB)receiving antiviral therapy.Methods:88 patients with chronic hepatitis B were randomly selected to receive antiviral therapy in our hospital from January 222 to October 2022.The patients were randomly divided into control group(n=44)and observation group(n=44).All patients received routine antiviral therapy during hospitalization.All patients were given routine antiviral treatment.The control group used routine nursing as an intervention method during the treatment period,and the observation group used continuous nursing management as an intervention method during the treatment period.The compliance of the two groups with antiviral treatment,liver fibrosis indicators before and after treatment,liver function indicators,incidence of adverse drug reactions,rehospitalization rate and negative rate of hepatitis B virus deoxyribonucleic acid(HBV DNA)were compared.Results:The total compliance of antiviral therapy in the observation group was significantly higher than that in the control group(P<0.05).There was no significant difference in liver fibrosis index and liver function index between the two groups before and after intervention(P>0.05).After intervention,the levels of each index in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse drug reactions between the two groups(P>0.05),and the readmission rate in the observation group was significantly lower than that in the control group(P<0.05).The rate of HBV DNA negative conversion in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:Continuous nursing management for patients with chronic hepatitis B treated with antiviral therapy can significantly improve the compliance with antiviral therapy,promote the improvement of liver function,and effectively reduce the readmission rate of patients.
出处
《黑龙江中医药》
2024年第1期172-174,共3页
Heilongjiang Journal of Traditional Chinese Medicine
关键词
慢性乙肝病毒
连续性护理管理
治疗依从性
肝功能
不良反应
再住院率
Chronic hepatitis B virus
Continuous Nursing Management
Treatment compliance
Liver function
Adverse reactions
Rehospitalization rate
作者简介
通讯作者:吴文裕
