摘要
本实验采用顺行、逆行及跨神经元追踪技术,对金黄地鼠丘脑网状核视部的纤维联系进行了实验观察。一、正常金黄地鼠4只,制成尼氏和Loyez染色的连续切片各4套,观察丘脑网状核(RT)的正常位置形态和范围。二、将^(3)H-Proline和^(3)H-Fucose注入动物一侧眼球(2只,存活期分别为10、15天)后,可见跨神经元标记于双侧RT的背尾侧部,但同侧标记甚少。三、将HRP分别注入丘脑后外侧核(LP)、外侧膝状体背核(LGd)和外侧膝状体腹核(LGv)(8只,存活期1天)后,分别在同侧RT的背尾侧份的背侧区、中份和腹侧区见有HRP标记神经元。四、将^(3)H-Proline和^(3)H-Leucine混合导入视皮质17区不同部位(3只,存活期1天)后,可见在各例的同侧RT的背尾侧部的整个吻尾范围内都有长形的标记点。当注射17区尾侧时,标记部位靠背侧,而注射区越近吻侧时,标记点亦越靠腹侧。五、将HRP注入上丘(6例)时,见RT有极少量标记。本文认为,RT的背尾侧部为核的视部,因为它与视皮质及一些已知的与视觉有关的核团,如后外侧丘脑核、外侧膝状体背核和腹核等都有联系;同时,由于它们之间有局部点对点的定位关系,故此核可能与特定的、有局部定位的视信息的调节有关。
The thalamic reticular nucleus(RT)is a sheet-like nucleus which surrounds the anterolateral aspect of the dorsal thalamus.In this study,we present data on the connections of the dorsocaudal portion of the RT in hamsters using anterograde,retrograde and transneuroual fiber tracing techniques.After injection of one eye with a mixture of^(3)H-proline and^(3)H-fucose(2 animals;10 and 15 days survival time),transneuronal label was located in the dorsocaudal portion of the RT(dc RT)on both sides of the thalamus.After separate injection of horseradish peroxidase(HRP)into the thalamic lateral posterior nucleus(LP),dorsal and ventral nuclei of the lateral geniculate body(LGd,LGv)(8 animals,one day survival time),HRP labelled neurons wereobserved in the dorsal,middle and ventral area of the ipsilateral dc RT respectively.A small iontophoretic injection of a mixture of^(3)H-proline and^(3)H-leucine was made into different sites of area 17 in each of 3 hamsters(one day survival time),in each case an elongated patch of label was located in nearly the entire rostrocaudal extent of the ipsilateral dc RT.A caudal Injection in area 17 resulted in labelling the dorsal area while a progressively more rostral injection resulted in labelling a more ventral area of the dc RT.Thus,the dorsocaudal portion of the RT can be defined as the visual portion of the nucleus because it has connections with many of the known visual centres,namely,the visual cortex,LP,LGd,LGv Furthermore,because of the topographic connection with area 17 and the visual thalamic nuclei,the notion that the dc RT as a nucleus which is capable of processing specific and localised visual information.should be considered.
作者
李之琨
任麟孙
苏国辉
Li Zhikun;Ren Linsun;Su Guohui(Department of Anatomy,Zhongshan Medical College,Guangzhou;Department of Anatomy,Faculty of Medicine,University of Hong Kong,Hong Kong,China)
出处
《解剖学报》
CAS
1984年第3期273-280,341,共9页
Acta Anatomica Sinica
基金
Supported by grants from University of Hong Kong and Wing Lung Bank and Pauline Chan Medical Rcsearch Funds.
作者简介
李之琨,is a China Medical Board Fellow on leave from Department of Anatomy,Zhongshan Medical College,Guangzhou;任麟孙,Ren Linsun(Jen,Ling Sun);苏国辉,Su Guohui(So,Kwok-fai)
