摘要
中缝背核在针剌镇痛过程中起重要作用。本文用HRP法,对猫前脑和脑干向中缝背核的纤维投射,作了进一步的研究。HRP注入中缝背核吻侧部后,在前脑双侧先导回皮质和梨状前区皮质V层出现较多被标记的锥体细胞;缰外侧核出现较密集且形态不一的标记细胞;下丘脑各区(视前区、外侧区、内侧区和后区)也出现散在的标记细胞。HRP注入中缝背核尾侧部后,除前脑出现标记细胞的部位与HRP注入吻侧部者相同外,在脑干中脑导水管周围灰质、蓝斑,其他中缝核(中央上核,中缝线形核和中缝大核)、臂旁内、外侧核及脑干网状结构等处,也观察到标记细胞。结果表明前脑皮质、缰外侧核、下丘脑各区均有纤维直接投射到中缝背核。中缝背核也接受来自中脑水管周围灰质、蓝斑、其他中缝核等核团的纤维投射;中缝背核吻侧部和尾侧部的传入投射,存在一定的局部定位关系,即中缝背核吻侧部只接受来自前脑的纤维投射,其尾侧部既接受来自前脑的纤维投射,也接受来自脑干的纤维投射。
Nucleus raphe dorsalis(RD)plays an important role in acupuncture analgesia.We carried on further studies on the projections of RD from the forebrain and brain stem of the cat by using a horseradish peroxidase(HRP)retrograde axonal transport method.We have observed the labeled neurons in layerⅤof the proreate gyrus,area prepyriformis,nucleus lateral habenular,and hypothalamic areas(preoptic,lateral,medial and posterior areas)when HRP was injected into the rostral part of the RD.The labeled neurons were giant pyriform in shape in prereate gyrus and area prepyriformis and various shapes in the lateral habenular and hypothalamic areas.We have also found the labeled neurons in the periaqueductal gray matter,locus coeruleus,lateral and medial parabrachial nuclei,other raphe nuclei(n.centralis superior,n.raphe magnus and n.linearis intermediate)and reticular formation of the brain stem when we injected HRP into the caudal part of the RD.This present results confirm that the fibers project to the RD directly from the forebrain cortex(proreate gyrus and area prepyriformis),latral habenular nucleus hypothalamic areas,periaqueductal gray matter,locus coeruleus and other raphe nuclei.We also have found that the afferent projections to the rostral part of the RD and the caudal part of the RD had different origins,that is,the rostral part receives fibers from the forebrain and the caudal part receives fibers not only from the forebrain,but also from the brain stem.The study provided a foundation for explaining acupuncture analgesia and physiological functions of RD.
作者
晋志高
范天生
Jin Zhigao;Fan Tiansheng(Department of Anatomy,Henan Medical College,Zhengzhou)
出处
《解剖学报》
CAS
1988年第1期30-36,115,共8页
Acta Anatomica Sinica
关键词
中缝背核
辣根过氧化物酶
猫
Raphe dorsalis
Horseradish peroxidase
Cat
