摘要
目的了解某社区体检人群三酰甘油水平的分布特点及其与高尿酸血症发病的相关性。方法以2018年北京某社区中老年健康体检人群为研究对象,探讨三酰甘油水平与高尿酸血症的关联性。结果共纳入研究对象634例,其中男性272例(42.9%),年龄45~89(62.1±11.3)岁。高三酰甘油血症69例(10.9%),高尿酸血症169例(26.7%)。多因素logistic回归模型结果显示:在调整年龄、性别、体质量指数(body mass index,BMI)分类、腰围、高密度脂蛋白胆固醇和血红蛋白等因素后,某社区体检人群三酰甘油水平每升高1 mmol/L,高尿酸血症的患病概率增加44.7%(OR=1.447,95%CI:1.175~1.781)。按性别分层分析,男性体检人群中三酰甘油水平每升高1 mmol/L,高尿酸血症的患病概率增加37.4%(OR=1.374,95%CI:1.054~1.791);女性体检人群中三酰甘油水平每升高1 mmol/L,高尿酸血症的患病概率增加64.8%(OR=1.648,95%CI:1.201~2.259)。结论三酰甘油水平与高尿酸血症患病风险有关。
Objective To investigate the level of triglyceride and the correlation between triglyceride level and hyperuricemia in community dwelling middle-aged and elderly people.Methods A cross-sectional data set of health examination population in a community in 2018 was analyzed to investigate the correlation between triglyceride level and hyperuricemia.Results A total of 634 middle-aged and elderly people were enrolled,including 272 males and 329 females,with age ranging from 45 to 89(62.1±11.3)years.Hypertriglyceridemia was found in 69(10.9%)cases and hyperuricemia was found in 169(26.7%)cases.Multivariate logistic regression analysis showed that the prevalence of hyperuricemia increased by 44.7%(OR=1.447,95%CI:1.175-1.781)with the increase of triglyceride level by 1 mmol/L after adjusting factors such as age,sex,BMI classification,waist circumference,high density lipoprotein cholesteroland hemoglobin.According to gender stratification analysis,the prevalence of hyperuricemia increased by 37.4%(OR=1.374,95%CI:1.054-1.791)with 1 mmol/L increase of triglyceride in male,and by 64.8%(OR=1.648,95%CI:1.201-2.259)with 1 mmol/L increase of triglyceride in female.Conclusion Increased triglycerides are associated with increased risk of uricemia in community dwelling middle-aged and elderly people.
作者
长征
何文
CHANG Zheng;HE Wen(61599 Military Outpatient Department,Beijing 100120,China)
出处
《解放军医学院学报》
CAS
2019年第11期1044-1047,1051,共5页
Academic Journal of Chinese PLA Medical School
关键词
中老年人
三酰甘油
高尿酸血症
middle-aged and elderly
triacylglycerol
hyperuricemia
作者简介
长征,男,硕士。研究方向:慢病防治。Email:chang_78@126.com;通信作者:何文,男,博士,医师。Email:hw3313279@163.com
