摘要
肿瘤型假体置换是重建肿瘤切除后骨缺损最常见的方式,而假体周围感染是导致假体失效最主要的原因之一。截肢是既往治疗肿瘤型假体周围感染常采用的方式,虽能较好控制感染,但术后功能较差,给患者带来了沉重的心理负担。保肢治疗主要方式包括清创灌洗、一期翻修、二期翻修等。清创灌洗和一期翻修具有耗时短、翻修术后功能较好的优点,但再感染发生率高;二期翻修虽然存在手术次数多、住院时间长、术后功能较差等问题,但感染控制效果明显优于一期翻修。本文就肿瘤型假体周围感染病因、诊断、预防以及治疗等方面的研究进展进行综述。
Megaprosthesis replacement is the most common way to reconstruct bone defects after tumor resection.Perimegaprosthetic infection(PMI)is one of the leading causes resulting in prosthesis failure.Amputation has been a common way to treat PMI in the past.Although the infection can be well controlled,the postoperative function is poor,thus bringing heavy psychological burden to patients.The pervasive methods of limb salvage treatment include debridement,antibiotics,irrigation and implant retention(DAIR),single-stage revision,two-stage revision,etc.DAIR and single-stage revision have the advantages of shorter operating time and better postoperative function,but the incidence of reinfection is quite high.On the contrary,the two-stage revision is much better than the single-stage revision in infection control despite more operations,longer hospital stay and poorer postoperative function.This article aims to review the etiology,diagnosis,prevention and treatment of PMI.
作者
李健雄
廖松
毕竟优
毕文志
LI Jianxiong;LIAO Song;BI Jingyou;BI Wenzhi(Department of Orthopedics,the First Medical Center,Chinese PLA General Hospital,Beijing,100853,China;Chinese PLA Medical School/Graduate School,Chinese PLA General Hospital,Beijing,100853,China)
出处
《解放军医学院学报》
CAS
2020年第4期399-403,共5页
Academic Journal of Chinese PLA Medical School
基金
军委后勤保障部卫生局军队保健专项科研课题(18BJZ29)
作者简介
李健雄,男,在读硕士。Email:ljianxiong301@163.com;通信作者:毕文志,男,博士,主任医师,博士生导师。Email:biwenzhi@sina.com
