摘要
目的分析大脑中动脉粥样硬化斑块在高分辨率磁共振成像(HRMRI)中的影像学特征与急性/亚急性缺血性卒中的相关性。方法用3.0 T磁共振对105例大脑中动脉粥样硬化的患者进行检查,采用优化的三维可变翻转角度快速自旋回波(SPACE)T1WI序列,观察大脑中动脉狭窄处斑块的HRMRI影像学特征。评价内容包括最小管腔面积、斑块负荷及斑块强化率等。将患者分为卒中组(发生急性/亚急性缺血性卒中)和非卒中组(未发生急性/亚急性缺血性卒中),使用卡方检验或独立样本t检验对两组患者的斑块特征进行统计学分析。结果105例患者中58例发生急性/亚急性缺血性卒中。卒中组40例患者见斑块内高信号;43例见管腔狭窄(管腔狭窄率<50%)。其中斑块内高信号(χ2=33.31,P<0.001)、最小管腔面积(t=2.755,P=0.007)和斑块强化率(t=8.573,P<0.001)与急性/亚急性缺血性卒中的发生具有相关性。两组之间管腔狭窄(管腔狭窄率<50%)及斑块负荷比较无统计学差异(P>0.05)。结论大脑中动脉粥样硬化斑块HRMRI影像学特征可以对急性/亚急性脑卒中进行一定程度的预测。
Objective To determine the relative contribution of imaging features by high-resolution magnetic resonance imaging(HRMRI)of middle cerebral artery atherosclerotic plaque to acute/subacute ischemic stroke.Methods 105 patients with middle cerebral artery atherosclerosis were examined by 3.0 T magnetic resonance.T1-weighted-sampling perfection with application of optimized contrasts using different flip angle evolution,T1 WI SPACE was used.The imaging features of plaques in middle cerebral artery were observed,including plaque burden,minimal luminal area,contrast enhancement ratio and so on.The imaging features between stroke group(patients with acute/subacute ischemic stroke)and non-stroke group(patients without acute/subacute ischemic stroke)were compared by Chi-square test or independent-samples t test.Results There were 58 of 105 patients with ischemic stroke.40 patients showed high signal in the stroke group;43 patients showed stenosis in the stroke group.The high signal(P<0.001),minimal luminal area(P=0.007),and contrast enhancement ratio(P<0.001)were associated with acute/subacute ischemic stroke.The stenosis and plaque burden had no significant difference between stroke group and non-stroke group(P>0.05).Conclusion The imaging features of plaques in middle cerebral artery can give a certain degree of acute/subacute stroke prediction.
作者
刘潇
蒋涛
宋焕
张继洋
LIU Xiao;JIANG Tao;SONG Huan(Department of Radiology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,P.R.China)
出处
《临床放射学杂志》
CSCD
北大核心
2020年第6期1041-1045,共5页
Journal of Clinical Radiology
关键词
高分辨率磁共振成像
大脑中动脉
动脉粥样硬化
缺血性卒中
High-resolution magnetic resonance imaging
Middle cerebral artery
Atherosclerosis
Ischemic stroke
作者简介
通讯作者:蒋涛
