摘要
目的探讨规范化序贯营养支持在老年大肠癌患者术后治疗中的临床应用效果。方法选取2014年1月至2018年12月南昌大学附属人民医院收治的123例老年大肠癌患者,根据术后营养支持方式的不同分为观察组(62例)和对照组(61例)。其中观察组术后采用规范化肠外+肠内序贯营养支持治疗,对照组以肠外营养向常规饮食过渡进行。观察比较两组患者术后第3、7天营养相关指标,术后恢复情况,以及营养支持相关并发症的发生情况。组间计量资料的比较采用t检验,计数资料的比较采用χ~2检验。结果术后第3天,观察组患者前白蛋白水平显著低于对照组(t=2.670,P<0.01);术后第7天,观察组患者前白蛋白水平、白蛋白水平明显高于对照组(t=2.344、2.677,P<0.05或0.01)。观察组患者术后肛门排气/排便时间明显短于对照组(t=2.113,P<0.05)。两组患者术后营养支持并发症发生率的差异无统计学意义(t=2.736,P>0.05)。结论规范化序贯营养支持治疗能有效改善老年大肠癌患者术后营养状态,促进术后胃肠功能恢复。
Objective To explore the effect of standardized sequential nutrition support in the postoperative treatment of elderly patients with colorectal cancer.Methods From January 2014 to September 2018,123 elderly patients with colorectal cancer admitted to the Affiliated People’s Hospital of Nanchagn Universiy were divided into group A(62 cases)and group B(61 cases).The group A received standardized parenteral and enteral sequential nutritional support treatment,while the group B received conventional parenteral nutrition after operation,then convert to a regular diet.To compare the nutrition related indicators,postoperative recovery,and related complications between the two groups.T test was used to compare the measurement data between the two groups,andχ~2 test was used to compare the count data.Results On the third day after operation,the level of prealbumin in group A was significantly lower than that in group B(t=2.670,P<0.01);on the seventh day after operation,the level of prealbumin and albumin in group A was significantly higher than that in group B(t=2.344,2.677,P<0.05 or P<0.01).The time of anal exhaust/defecation in group A was significantly shorter than that in group B(t=2.113,P<0.05).There was no significant difference in the incidence of postoperative nutritional support complications between the two groups(t=2.736,P>0.05).Conclusion Standardized sequential nutritional support therapy for elderly patients with colorectal cancer can effectively improve postoperative nutritional status and enhance postoperative recovery of gastrointestinal function.
作者
周辉
李坚
王俊
华丽
袁喜红
周凯
Zhou Hui;Li Jian;Wang Jun;Hua Li;Yuan Xihong;Zhou Kai(Department of General Surgery,the Affiliated People's Hospital of Nanchagn Universiy,Nanchang 330006,China)
出处
《中华老年病研究电子杂志》
2019年第3期38-41,共4页
Chinese Journal of Geriatrics Research(Electronic Edition)
基金
江西省卫生和计划生育委员会普通计划课题(20151021).
关键词
大肠癌
营养支持
序贯
老年人
Colorectal cancer
Nutritional support
Sequential
Aged
作者简介
通信作者:袁喜红,Email:yuanxihong@126.com
