摘要
目的通过对清痰宁神方合乌灵胶囊的临床观察,旨在为中风病失眠患者提供一种疗效确切,无明显不良反应,易于推广,经济实用的治疗方案;为清痰宁神方合乌灵胶囊治疗痰热扰神型中风病失眠的推广应用提供临床依据。方法观察痰热扰神型中风病失眠患者60例,治疗组和对照组各30例。两组其他治疗相同,治疗均为60 d结束疗程,然后进行治疗前后中医证候(TCMSS)评分、神经功能缺损程度(NFDD)评分、匹兹堡睡眠质量指数(PSQI)评分,比较两组的治疗效果。结果两组患者TCMSS治疗组总有效率为93.33%(28/30),对照组总有效率为63.33%(19/30),治疗组疗效优于对照组。两组患者NFDD、PSQI评分比较:治疗前两组间差异无统计学意义,治疗15 d后治疗组与对照组比较差异有统计学意义,治疗30 d、60 d后与对照组比较,差异有极显著统计学意义,治疗组疗效优于对照组。结论清痰宁神方合乌灵胶囊治疗中风病失眠的临床疗效明显优于对照组,可明显改善患者临床症状、神经功能缺损积分、睡眠质量、焦虑情绪,提高患者生存质量,临床疗效显著。
Objective Through the clinical observation of Qingtan Ningshen Formula(清痰宁神方)and Wuling Capsule(乌灵胶囊),this paper aims to provide an economic and practical treatment scheme with definite curative effect,no obvious adverse reactions,easy to promote for stroke patients with insomnia and clinical basis for the popularization and application of Qingtan Ningshen Formula and Wuling Capsule in the treatment of insomnia caused by phlegm-heat disturbing spirit type of apoplexy.Methods Sixty patients with insomnia caused by phlegm-heat disturbing spirit type of apoplexy were observed,30 cases in treatment group and 30 cases in control group.The other treatments were the same in both groups,and the treatment lasted for 60 days.The TCM syndrome(TCMSS)scores before and after treatment were assessed.The neurologic impairment degree(NFDD)score,Pittsburgh Sleep Quality Index(PSQI)score and the therapeutic effects of the two groups were compared.Results The total effective rate of TCMSS in the two groups was 93.33%(28/30)and that of the control group was 63.33%(19/30),and the therapeutic effect of the treatment group was better than that of the control group.NFDD and PSQI scores had no significant difference between the two groups before treatment.After 15 days of treatment,the difference between the treatment group and the control group was significant.After 30 and 60 days of treatment,the difference between the treatment group and the control group was very significant.The treatment group was better than the control group.Conclusion The clinical effect of Qingtan Ningshen Formula and Wuling Capsule on apoplectic insomnia is obviously better than that of the control group.It can obviously improve the patients'clinical symptoms,scores of nerve function defect,sleep quality and anxiety and the quality of life of patients.The clinical efficacy is significant.
作者
吴玉红
王松龄
WU Yuhong;WANG Songling(The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450002,Henan,China)
出处
《辽宁中医杂志》
CAS
2021年第11期113-116,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金重点项目(81230086)
国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人教函[2018]134号)
关键词
王松龄
痰热扰神型
清痰宁神方
中风病失眠
WANG Songling
phlegm-heat disturbing spirit type
Qingtan Ningshen Formula(清痰宁神方)
apoplectic insomnia
作者简介
吴玉红(1977-),女,河南郑州人,主治医师,硕士,研究方向:中西医结合治疗睡眠障碍、精神类疾病的临床与研究;通讯作者:王松龄(1946-),男,河南西平人,主任中医师,研究方向:中西医结合治疗睡眠障碍、脑血管疾病的临床与研究,E-mail:13393732732@126.com。