摘要
Purpose:Individual chronotypes are reported to be closely associated with mood,health status,and even disease progression.However,no reports of chronotype distribution in the Chinese population have been made available to date.Methods:We performed a chronotype survey using the classic Morningness–Eveningness Questionnaire both online and offline.The webpage-based online survey was distributed via a social network application on mobile phones.The offline survey was distributed to local primary and middle schools.A total of 9476 questionnaires were collected,of which 8395 were valid.The mean age of the participants was 30.38±11.47 years,and 37.38%were male.Results:Overall,the Chinese chronotypes showed a near-normal distribution with a slight shift toward eveningness.When analyzed in different age groups,the overall Chinese population was shown to be"latest"in their early twenties.In the young population,two significant points of change in chronotype were identified at the ages of 10 and 16 years.The chronotype composition remained relatively stable during early adulthood(from 17 to 28 years of age).Conclusion:This study generated the first overview of chronotype distribution in the Chinese population and will serve as essential background data for future studies.
基金
supported by grants from the National Natural Science Foundation of China(No.31630091 awarded to Ying Xu,No.81600380 awarded to F.Z.,No.31600958 awarded to Z.L.)
National Center for International Research(No.2017B01012)
作者简介
Zhiwei Liu received his Ph.D.degree from Model Animal Research Center of Nanjing University,China(2014).Then he has been working as a lecturer at Cambridge‐Suda Genomic Resource Center,Soochow University.His research interests focus on the cross‐talk between circadian clock and other physiological systems.E‐mail:zwliu@suda.edu.cn,These authors contributed equally to this work;Yingying Dong received her Ph.D.degree from Model Animal Research Center of Nanjing University,China(2011)and then received her postdoctoral training in Nankai University.She is now an associate professor of Cambridge‐Suda Genomic Resource Center,Soochow University.Her current research interests focus on the regulatory mechanisms of circadian rhythms and reproductive development.E‐mail:yydong@suda.edu.cn,These authors contributed equally to this work;Ying Xu received her M.D.degree in pathology from Saitama Medical School in Japan(1996),and Ph.D.degree in cell biology from the University of Tokyo in Japan(2001).She then conducted postdoctoral research in the University of California,San Francisco(2003–2006).She was a professor in Nanjing University(2006–2014)and is currently the director of Cambridge‐Suda Genomic Resource Center,Soochow University.Her research interests focus on the regulatory mechanism of circadian rhythms and the relationship between circadian clock and homeostasis.E‐mail:yingxu@suda.edu.cn;Corresponding author:Fei Zhou received his Ph.D.degree in biology from Model Animal Research Center of Nanjing University,China(2011).He then worked as a senior scientist in WuXi AppTec(2011–2014)and is now an associate professor of Cambridge‐Suda Genomic Resource Center,Soochow University.His research interests focus on the regulatory roles of circadian rhythm in cardiovascular system.E‐mail:fzhou@suda.edu.cn
