摘要
细胞焦亡作为一种新的程序性死亡方式,其在前列腺癌发生与发展中有重要作用,而且针对细胞焦亡途径的靶向药物可以作为一种新的治疗方式在未来起到极大的影响,但是细胞焦亡的具体机制仍然还不明确,因此还需大量研究进行深入探索。本文就近几年来细胞焦亡在前列腺癌中的作用作一综述,主要包括焦亡的发生机制、其在前列腺癌发生发展中的作用及其临床应用,为临床工作者提供一个新的治疗及药物研发策略。
Pyroptosis,as a new programmed death mode,plays an important role in the development and progression of prostate cancer,and the drugs targeting the pyroptosis pathway,as a new therapeutic strategy,may produce a significant influence on the treatment of prostate cancer.However,the precise mechanism of cellular pyroptosis remains unclear,necessitating further investigation.This paper presents a summary of the role of cellular pyroptosis in prostate cancer over recent years.It includes a discussion of the mechanism of pyroptosis,its role in prostate cancer development,and its clinical applications.This will provide clinicians with a new strategy for treatment and drug development.
作者
赵琦(综述)
左康为(综述)
李卫平(审校)
ZHAO Qi;ZUO Kang-wei;LI Wei-ping(The First Clinical Medical College of Lanzhou University,Lanzhou,Gansu 730000,China;Department of Urology,The First Hospital of Lanzhou University,Lanzhou,Gansu 730000,China)
出处
《中华男科学杂志》
CAS
CSCD
2024年第2期180-183,共4页
National Journal of Andrology
基金
甘肃省自然科学基金(22JR5RA912)
作者简介
赵琦(1999-),男,甘肃金昌市人,硕士研究生,从事泌尿外科专业;通讯作者:李卫平,Email:liweipingmail@163.com
