摘要
目的分析对孕妇进行无创DNA检测和羊水细胞染色体检查的临床意义。方法将2018年1月—2019年1月期间我院收治的100例孕妇作为研究对象,孕妇均具有高龄,出生缺陷生育史和产前筛查高风险等特点,患者均进行无创DNA检测和羊水细胞染色体检查。对比两种方式的诊断结果。结果100例患者中共计10例患者染色体异常,羊水细胞染色体检查检出率为100%(10/10),无创DNA检测检出率为90%(9/10),两种检测方式检出率无统计学意义(P>0.05)。结论无创DNA检测和羊水细胞染色体检查均属于检查胎儿染色体异常的重要手段,无创DNA检测具有无创,准确率高等优势,使用价值高。
Objective To analyze the clinical significance of non-invasive DNA detection and amniotic fluid chromosome examination in pregnant women.Methods 100 pregnant women admitted to our hospital from January 2018 to January 2019 were studied.The pregnant women were all old,with birth defects and high risk of prenatal screening.The patients were tested for non-invasive DNA and amniotic fluid chromosomes.Compared the diagnosis results of the two methods.Results A total of 10 patients out of 100 patients had chromosomal abnormalities.Rate of amniotic fluid chromosomes was 100%(10/10),and the detection rate of non-invasive DNA detection was 90%(9/10).The rate of two detection methods was not statistically significant(P>0.05).Conclusion Non-invasive DNA detection and amniotic fluid cell chromosome examination are important methods for detecting fetal chromosomal abnormalities.Non-invasive DNA detection has the advantages of non-invasiveness and high accuracy,and its use value is high.
作者
龙冠现
LONG Guanxian(Department of Clinical Laboratory,Chenzhou Maternal and Child Health Hospital,Chenzhou Hu'nan 423000,China)
出处
《中国卫生标准管理》
2020年第3期116-118,共3页
China Health Standard Management
关键词
孕妇
无创DNA检测
羊水细胞
染色体
诊断
胎儿
pregnant women
non-invasive DNA detection
amniocytes
chromosome
diagnosis
fetus
