摘要
目的探讨纳布啡对硬膜外阻滞分娩镇痛时布比卡因最低有效的影响。方法选取2018年5月—2019年10月在河南省漯河市中心医院采用硬膜外阻滞进行分娩镇痛的96例产妇作为本研究对象,随机分为研究组与对照组,每组48例。对照组进行布比卡因硬膜外泵注,研究组在对照组的基础上进行纳布啡注射。比较两组产妇的血流动力学指标,治疗后的Bromage评分以及镇痛前后的VAS评分。结果两组产妇的最低血压、心率以及胎儿胎心检测差异无统计学意义(P>0.05);研究组的Bromage评分为0分的产妇高于对照组(P<0.05);研究组镇痛后5 min、30 min以及60 min的VAS评分均低于对照组(P<0.05)。结论采用纳布啡复合较低浓度的布比卡因效果相对较好,对产妇运动神经的影响相对较小,并且不会对产妇的血流动力学产生影响,安全性较高,同时能够促使产妇镇痛的时间显著降低,利于临床应用及推广。
Objective To investigate the effect of nalbuphine on bupivacaine in epidural analgesia.Methods From May 2018 October 2019,96 parturient women who underwent epidural anesthesia for labor analgesia in Henan Luohe Central Hospital were selected as the subjects of this study,and were randomly divided into study group and control group.Epidural pump of bupivacaine in the control group,and the research group received nalbuphine injection on the basis of the control group.Hemodynamic indexes,Bromage scores after treatment and VAS scores before and after analgesia were compared between the two groups.Results There was no significant difference in lowest blood pressure,heart rate and fetal heart between the two groups(P>0.05).The Bromage score of the study group was higher than that of the control group(P<0.05).VAS scores at 5 min,30 min and 60 min after analgesia in the study group were lower than those in the control group(P<0.05).Conclusion The use of bupivacaine combined with nalbuphine at a lower concentration has a relatively good effect,has a relatively small effect on the motor nerves of the maternal,and does not affect the hemodynamics of the maternal.It is safer.Maternal analgesia time is significantly reduced,which is conducive to clinical application and promotion.
作者
李永强
吴悠
崔魁
白娜
李宪营
张清伟
孙素丽
LI Yongqiang;WU You;CUI Kui;BAI Na;LI Xianying;ZHANG Qingwei;SUN Suli(Henan Luohe Central Hospital,Luohe 462000,China)
出处
《中国全科医学》
CAS
北大核心
2020年第S01期145-147,共3页
Chinese General Practice
