摘要
目的探讨2型糖尿病早期肾病诊断中运用尿微量白蛋白和血清视黄醇结合蛋白的临床效果。方法选择2018年2月—2019年4月期间河南大学第一附属医院收治的150例2型糖尿病患者为研究对象,再选择同期来本院体检的健康者100例为对照组,分别检测两组的血清RBP和尿微量白蛋白,比较分析两组检测结果。结果与对照组相比,观察组的mALB和RBP水平均较高,组间比较差异有统计学意义(P<0.05);同时,相比较单纯T2DM组而言,T2DM合并DN组的RBP和mALB水平均较高,组间比较差异有统计学意义(P<0.05)。结论临床上给予2型糖尿病患者血清RBP联合尿微量白蛋白检测有助于诊断早期肾病。
Objective To investigate the clinical effect of urinary microalbumin and serum RBP in the diagnosis of early nephropathy in type 2 diabetes mellitus.Methods 150 patients with type 2 diabetes in First Affiliated Hospital of Henan University from february 2018 to april 2019 were selected as the study subjects,and 100 healthy patients who came to the hospital for physical examination in the same period were selected as the control group,and the serum RBP and urine microalbumin of the two groups were detected respectively.Results Compared with the control group,the mALB and RBP levels of the observation group were higher,and the difference between the groups was significant(P<0.05).The RBP and mALB levels were higher in T2DM group(P<0.05).Conclusion Serum RBP combined with urinary microalbumin in patients with type 2 diabetes mellitus is helpful to diagnose early nephropathy.
作者
常杰
CHANG Jie(First Affiliated Hospital of Henan University,Kaifeng 475000,China)
出处
《中国全科医学》
CAS
北大核心
2020年第S02期132-133,共2页
Chinese General Practice
基金
2012年开封市科技局项目(1203113)
