摘要
目的探讨崇明东部地区幽门螺杆菌(Hp)感染率调查及其危险因素的logstic回归分析。方法随机抽取2020年6月-2021年5月在上海市崇明东部地区学校、医院、企事业单位等不同人群的资料,调查总人数1326人。对所有研究对象进行Hp检测和呼气试验检测,分析总感染率及不同年龄组Hp感染结果,Hp感染与社会经济状态、生活习惯相关的危险因素分析,并对单因素分析中与Hp感染有关的因素和可能影响Hp感染的因素进行logistics回归分析。结果1326名研究对象中Hp阳性862例,总感染率为65.00%。15~<25岁Hp感染率最低,25~<35岁Hp感染率接近70%高峰,之后稍有回落再逐渐升高。农民、医护人员、无职业者Hp感染率高于其他职业(χ^(2)=12.900,P<0.05),家庭收入4万元以上的人群Hp感染率低于4万元以下人群(χ^(2)=16.655,P<0.05)。离婚的Hp感染率高于未婚和已婚人群,小学及以下受教育程度Hp感染率高于其他人群,但差异均无统计学意义(P>0.05)。居住在市区和郊区的Hp感染率差别不大。吸烟、饮酒、饮食种类、饮食咸淡、家养宠物、合用茶杯、合用牙缸与Hp感染无关,生食蔬菜水果、生食前不洗、家庭碗筷用洗洁精清洗等习惯人群Hp感染率更高。Logistics回归分析显示,Hp感染与接受抗Hp治疗成负相关,进食生蔬菜水果不清洗、家庭经济收入、年龄均是Hp感染的危险因素(P=0.01、0.02、0.02)。结论崇明东部地区Hp感染率较高,且Hp感染与社会经济状况和部分家庭及个人饮食卫生密切相关。
Objective To investigate the infection rate of Helicobacter pylori(Hp)and its risk factors in the east of Chongming.Methods Random sampling from June 2020 to May 2021,a sampling survey was conducted in schools,hospitals,enterprises and institutions in the eastern part of Chongming,Shanghai.The total number of people surveyed was1326.Hp detection and breath test were carried out on all subjects;the total infection rate and Hp infection results of different age groups were analyzed,and the risk factors related to Hp infection,socio-economic status and living habits were analyzed.The factors related to Hp infection and the factors that might affect Hp infection in univariate analysis were analyzed by logistic regression.Results The total Hp infection rate of 1326 subjects was 65.00%(862).The Hp infection rate of 15-<25 years old was the lowest;the Hp infection rate of 25-<35 years old was close to the peak of 70%,and then it dropped slightly and then rises gradually with age.The Hp infection rate of farmers,medical staff and unemployed was higher than that of other occupations(χ^(2)=12.900,P<0.05),and the Hp infection rate of people with family income of more than 40000 yuan was lower than that of people with family income of less than 40000 yuan(χ^(2)=16.655,P<0.05).The Hp infection rate of divorced people was higher than that of unmarried and married people.The Hp infection rate of people with primary school and below education level was higher than that of people with higher education level,but the difference was not statistically significant(P>0.05).Smoking,drinking,type of diet,salty diet,domestic pets,sharing tea cups and dental bowls were not correlated with Hp infection.The habitual people such as eating raw vegetables and fruits,not washing before eating raw,and whether household dishes and chopsticks were cleaned with detergent showed a higher Hp infection rate.Logistic regression analysis showed that Hp infection was negatively correlated with anti Hp treatment.Eating raw vegetables and fruits without cleaning,family income,gender and age were the risk factors of Hp infection(P=0.01,0.02,0.02).Conclusion The Hp infection rate was high in the east of Chongming,and Hp infection was closely related to socio-economic status and dietary hygiene of some families and individuals.
作者
周柳柳
郭峰健
施扬利
孙晓敏
ZHOU Liu⁃liu;GUO Feng⁃jian;SHI Yang⁃li;SUN Xiao⁃min(Department of Gastroenterology,Chongming Branch of Shanghai Tenth People's Hospital,Shanghai 202157,China)
出处
《热带医学杂志》
CAS
2022年第7期1010-1013,1021,共5页
Journal of Tropical Medicine
基金
上海市崇明区“可持续发展科技创新行动计划”项目(CKY2020-23)
作者简介
周柳柳(1984-),女,本科,从事幽门螺旋杆菌的防治方面研究;通信作者:孙晓敏,E⁃mail:897986343@qq.com
