摘要
肠道菌群已成为影响2型糖尿病的重要环境因素,菌群紊乱所导致的宿主能量稳态失衡参与了2型糖尿病的发生与发展,鉴于肠道菌群结构的可塑性,调节肠道菌群开辟了2型糖尿病防治的新途径。中医学认为,脾胃功能失调与消渴病(2型糖尿病)关系最为密切,其中,胃强是引起机体胃肠机能紊乱而导致2型糖尿病的重要病机。中医胃强与肠道菌群存在交互影响,二者共同助推了疾病的进程。因此,基于中医胃强与肠道菌群交互视角审视2型糖尿病的临床辨治具有重要意义。
The gut microbiota has become an important environmental factor affecting type 2 diabetes mellitus(T2 DM),and the imbalance of host energy homeostasis caused by gut microbiota is involved in the development and progression of T2 DM.Given the plasticity of the gut microbiota structure,regulating the gut microbiota opens up new avenues for the prevention and treatment of T2 DM.According to traditional Chinese medicine,the dysfunction of spleen and stomach is most closely related to Xiao Ke(T2 DM),among them,“Stomach Excess”is an important pathogenesis of T2 DM caused by gastrointestinal dysfunction.There is an interactive relationship between TCM“Stomach Excess”and gut microbiota,and the two factors together contribute to the disease process.Therefore,it is important to examine the clinical management of T2 DM based on the perspective of the interaction between TCM“Stomach Excess”and gut microbiota.
作者
陈源
李振华
张博荀
杨茂艺
许趁意
岳仁宋
CHEN Yuan;LI Zhenhua;ZHANG Boxun(Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 712046,China;The Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 712000,China;The Teaching Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu Sichuan 610072,China)
出处
《四川中医》
2022年第3期1-3,共3页
Journal of Sichuan of Traditional Chinese Medicine
基金
国家自然科学基金(编号:81774279)
陕西省中医药管理局科研项目(编号:2021-ZZ-JC004)
陕西省科技厅项目(编号:2022JM-495)
陕西中医药大学校级科研项目(编号:2021GP22)
陕西中医药大学博士科研启动金项目(编号:303/17102032041)
关键词
2型糖尿病
胃强
肠道菌群
交互
Type 2diabetes mellitus
“Stomach Excess”
Gut microbiota
Interaction
作者简介
第一作者:陈源,医学博士,主要从事内分泌代谢性疾病的中医药防治研究,E-mail:chenyuan1371@126.com;通讯作者:岳仁宋,主任医师,四川省名中医,硕/博士研究生导师,长期从事中医药防治内分泌代谢性疾病的临床与基础研究,Tel:028-87780627。
