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基于“开玄府—通络脉”理论探究三甲散治疗肝纤维化 被引量:5

Exploring the Treatment of Liver Fibrosis with Sanjia Powder Based on the Theory of “Opening Xuanfu-Relaxing Collaterals”
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摘要 玄府-络脉是人体的细微结构,二者共同构成机体微观结构的完整性,共同维系着周身气血的有序运行。玄府贵为开阖,开阖功能正常,能固护络脉中精微的运输,络脉中的血液可以渗贯于玄府之中,络脉与玄府通畅,则气血运行正常。中医认为肝纤维化为痰瘀留滞肝脏,肝络瘀阻,玄府闭塞,络脉不通而致。而肝纤维化的发生与玄府-络脉密切相关,但目前对玄府、络脉的研究相关性较少。三甲散在临床上治疗肝纤维化疗效显著,笔者欲通过开通玄府、化瘀通络的观点论述三甲散对肝纤维化的治疗作用,从而对治疗肝纤维化有着积极的意义。 Xuanfu-collaterals is the fine structure of human body,the two together constitute the integrity of the body’s microstructure,jointly held a general ordered operation of Qi and blood,the Xuanfu expensive for open closed,open close function is normal,can the transportation of solid protection of collaterals in subtle,collaterals blood seeped in the penetration in the Xuanfu,collaterals and Xuanfu unobstructed,blood running normally.Traditional Chinese medicine believes that liver fiber into phlegm stasis stagnation liver,liver collateral stasis block,Xuanfu occlusion,bypass.The occurrence of liver fibrosis is closely related to the Xuanfu and Xuanfu complex,but the correlation of the Xuanfu and the complex is less at present.Sanjia Powder has a significant clinical effect in the treatment of liver fibrosis.The author would like to discuss the therapeutic effect of Sanjia Powder on liver fibrosis by opening Xuanfu and removing blood stasis and relaxing collaterals,so as to have a positive significance in the treatment of liver fibrosis.
作者 王蝶 张宝成 王宝家 钟康骏 陈佳逸 高永翔 WANG Die;ZHANG Baocheng;WANG Baojia(Chengdu University of Traditional Chinese Medicine,Chengdu Sichuan 610075,China;The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu Sichuan 610072,China)
出处 《四川中医》 2022年第4期15-18,共4页 Journal of Sichuan of Traditional Chinese Medicine
基金 国家自然科学基金项目(项目编号:81904080,项目名称:基于肝窦内皮细胞的窗孔调控探究开通玄府抗肝纤维化的分子机构)
关键词 肝纤维化 玄府 络脉 瘀血 Liver fibrosis Xuanfu Collaterals Blood stasis
作者简介 通讯作者:高永翔,成都中医药大学教授,博士研究生导师,博士,主要从事中药免疫药理毒理研究、中医药防治风湿免疫病的转化医学研究工作,E-mail:drgaoyx@cdutcm.edu.cn
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