摘要
目的:探讨支原体肺炎(MPP)患者中医证型分布及其与降钙素原(PCT)、淋巴细胞绝对值(LYM)的相关性。方法:选取2019年6月-2020年12月期间于我院收治的106例MPP患者作为研究对象,分析患者的中医证型分布,比较不同中医证型患者的PCT、LYM水平、肺炎严重指数(PSI)评分、CURB-65评分等临床资料,分析PCT、LYM与PSI、CURB-65评分之间的关系。结果:106例MPP患者主要为痰热壅肺证、风热犯肺证和肺胃热盛证,分别占比36.79%、22.64%和19.81%;三组在性别、病程、年龄段分布方面无明显差异(P>0.05),但痰热壅肺证患者咳嗽时间高于风热犯肺证和肺胃热盛证患者(P<0.05);三组患者PCT水平、PSI、CURB-65评分由高到低依次为:痰热壅肺证、肺胃热盛证、风热犯肺证,差异有统计学意义(P<0.05);痰热壅肺证患者LYM水平均明显低于风热犯肺证和肺胃热盛证患者(P<0.05);相关性分析结果显示,MPP患者血清PCT水平与PSI、CURB-65评分之间分别互为正相关性(P<0.05)。结论:106例MPP患者中医证型以痰热壅肺证、风热犯肺证和肺胃热盛证为主,其中医证型与PCT、LYM水平和病情严重程度有关,PCT、LYM对于MPP患者中医辨证和病情判断具有一定的参考价值。
Objective:To explore the distribution of TCM syndromes and their correlation with procalcitonin(PCT)and absolute value of lymphocyte(LYM)in patients with mycoplasma pneumoniae pneumonia(MPP).Methods:A total of 106 patients with MPP admitted to the hospital were enrolled as the research objects between June 2019 and December 2020.The distribution of TCM syndromes was analyzed.The levels of PCT and LYM,scores of pneumonia severity index(PSI)and CURB-65 in patients with different TCM syndromes were compared.The relationship between PCT,LYM levels and PSI,CURB-65 scores was analyzed.Results:Of the 106 patients with MPP,the main TCM syndromes included phlegm-heat obstructing lung,wind-heat invading lung and lung-stomach hotness,(36.79%,22.64%,19.81%).The difference among the three groups in gender,disease course and distribution of age groups was not statistically significant(P>0.05).The cough time in patients with phlegm-heat obstructing lung was longer than that with wind-heat invading lung and lung-stomach hotness(P<0.05).PCT level,the scores of PSI and CURB-65 were the highest in patients with phlegm-heat obstructing lung,followed by lung-stomach hotness and wind-heat invading lung(P<0.05).LYM level in patients with phlegm-heat obstructing lung was significantly lower than that with wind-heat invading lung and lung-stomach hotness(P<0.05).The results of correlation analysis showed that level of serum PCT was positively correlated with PSI and CURB-65 scores(P<0.05).Conclusion:Of the 106 patients with MPP,the main TCM syndromes include phlegm-heat obstructing lung,wind-heat invading lung and lung-stomach hotness.TCM syndromes are related to PCT,LYM and disease severity.PCT and LYM are of certain reference value for TCM syndrome differentiation and conditions determination in MPP patients.
作者
宋秋玲
宋秀丽
SONG Qiuling;SONG Xiuli(Department of Medical Laboratory Science,National Hospital of Enshi Tujia and Miao Autonomous Prefecture,Enshi Hubei 445000,China;Department of Infectious Diseases,National Hospital of Enshi Tujia and Miao Autonomous Prefecture,Enshi Hubei 445000,China)
出处
《四川中医》
2022年第8期60-63,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
湖北省科技厅资助项目(编号:2012DGA18832)
关键词
支原体肺炎
中医证型
降钙素原
淋巴细胞绝对值
相关性
Mycoplasma pneumoniae pneumonia
TCM syndrome
Procalcitonin
Absolute value of lymphocyte
Correlation
作者简介
第一作者:宋秋玲,本科,主管技师,研究方向:临床检验,E-mail:bmhhw17@163.com;通讯作者:宋秀丽,本科,主任医师,研究方向:呼吸道传染疾病诊疗。
