摘要
目的:探究玫瑰痤疮协定方靶向雾化治疗对面部玫瑰痤疮患者生活质量影响。方法:纳入169例面部玫瑰痤疮患者,均由我院2020年1月~2021年2月收治,采取随机数字表法将患者分成两组,对照组患者(85例)激光治疗及常规干预,观察组患者(84例)治疗及干预同对照组,同时联合玫瑰痤疮协定方靶向雾化治疗,比较各组患者疗效、干预前后中医证候(红斑、丘疹脓疱、烧灼瘙痒感、口干便干等)积分变化、皮肤红斑指数E值及血清白细胞介素-37(IL-37)水平变化、痤疮特异性生活质量量表(Acne-QOL)评分变化、干预后患者面部美观评分及患者满意度评分。结果:较对照组(89.41%),观察组患者(97.62%)治疗总有效率更高,P<0.05;干预前,两组患者中医证候(红斑、丘疹脓疱、烧灼瘙痒感、口干便干等)积分、皮肤红斑指数E值、IL-37水平、Acne-QOL评分比较,P>0.05,干预后各组患者中医证候(红斑、丘疹脓疱、烧灼瘙痒感、口干便干等)积分、皮肤红斑指数E值、IL-37水平、Acne-QOL评分均改善,观察组患者干预后中医证候(红斑、丘疹脓疱、烧灼瘙痒感、口干便干等)积分、皮肤红斑指数E值、IL-37水平、Acne-QOL评分优于对照组,P<0.05;观察组患者干预后面部美观评分及患者满意度评分均高于对照组,P<0.05。结论:玫瑰痤疮协定方靶向雾化治疗对面部玫瑰痤疮效果良好,患者总有效率提升,症状改善,生活质量提升,面部美观,患者十分满意,值得应用。
Objective:To explore the effect of targeted atomization of Rosa acne protocol prescription on the quality of life of patients with facial Rosa acne.Methods:A total of 169 patients with facial rosacea were enrolled and treated in our hospital from January 2020 to February 2021.The patients were divided into two groups by the random number table method,a controlled group(n=85)received laser treatment and conventional intervention,an observation group(n=84)received treatment and intervention the same as the controlled group,and combined with targeted atomization of rosacea protocol prescription.Comparison of the curative effect and TCM syndrome between the two groups before and after the intervention(erythema,papules,pustules burning itching,dry mouth and dry,etc.)changes,skin erythema index E values and serum interleukin-37(IL-37)level changes,Acne specific quality of life scale(Acne-QOL)a grade change,after intervention in patients with facial aesthetics and patient satisfaction scores.Results:Compared with the controlled group(89.41%),the total effective rate of the observation group(97.62%)was higher,P<0.05;Before intervention,scores of TCM syndromes(erythema,papular pustules,burning pruritus,dry mouth and stool),skin erythema index E value,IL-37 level and acne-QOL score were compared between the two groups(P>0.05).After intervention,TCM syndrome score(erythema,papular pustules,burning pruritus,dry mouth and stool,etc.),skin erythema index E value,IL-37 level and acne-QOL score were all improved in each group.After intervention,the scores of TCM syndrome(erythema,papular pustules,burning pruritus,dry mouth and stool,etc.),skin erythema index E value,IL-37 level and acne-QOL score in the observation group were better than those in the controlled group(P<0.05).The facial aesthetic score and patient satisfaction score in the observation group were higher than those in the controlled group after intervention,P<0.05.Conclusion:Roseacne protocol targeted atomization treatment has good effect on facial roseacne,the total effective rate of patients is improved,the symptoms are improved,the quality of life is improved,the facial beauty is improved,the patients are very satisfied,worthy of application.
作者
刘萍
姚倩
瓦庆彪
何梅
刘立凡
龚亚莉
LIU Ping;YAO Qian;WA Qingbiao(Department of Medicine and Aesthetics,the Second People's Hospital of Chengdu City,Chengdu Sichuan 610000,China)
出处
《四川中医》
2022年第11期179-183,共5页
Journal of Sichuan of Traditional Chinese Medicine
基金
四川省科技厅项目(编号:2016SZ0062)
关键词
面部玫瑰痤疮
玫瑰痤疮协定方
靶向雾化
疗效
生活质量
中医证候
Facial rosacea
Rose acne protocol
Targeted atomization
Curative effect
Quality of life
Traditional Chinese medicine syndrome
