摘要
近视形成机制极为复杂,近年来提出的“巩膜缺氧学说”认为巩膜缺氧、重塑可能是近视形成的关键因素,而脉络膜厚度及脉络膜血流变化可能在视网膜巩膜通路中发挥重要作用参与调节眼球生长。研究发现脉络膜变薄伴随着近视的发生和发展,而角膜塑形镜、阿托品滴眼液和环境光暴露等干预措施可增加脉络膜厚度,提示脉络膜增厚是近视进展的保护因素。因此,本文对近视与脉络膜的关系及近视的光学、药物和环境干预措施对脉络膜产生的变化进行综述,旨在更好了解此类非手术的干预措施对脉络膜的影响。
The mechanisms of development of myopia are extremely complex.The“scleral hypoxia theory”proposed in recent years suggests that scleral hypoxia and remodeling may be a key factor in the development of myopia.Choroidal thickness and choroidal blood flow changes may play an important role in the retinal scleral pathway signaling and participate in the regulation of eyeball growth.Studies have shown choroidal thinning to be associated with the onset and development of myopia.Interventions such as orthokeratology,atropine eye drops and exposure to ambient light can increase choroidal thickness,suggesting that choroidal thickening is a protective factor for myopia progression.Therefore,this paper reviews the relationship between myopia and choroid,and the changes induced in the choroid by optical,drug and environmental interventions used for improvement of myopia,aiming to better understand the effects of such non⁃surgical interventions on choroid.
作者
张莉苑
钟定娟
王华
ZHANG Liyuan;ZHONG Dingjuan;WANG Hua(Department of Optometry and Ophthalmology,Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University,Changsha 410005,Hunan,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2024年第4期149-153,165,共6页
Journal of Otolaryngology and Ophthalmology of Shandong University
基金
湖南创新型省份建设专项任务书(2020SK2118)
关键词
近视
脉络膜厚度
脉络膜血流
干预措施
Myopia
Choroidal thickness
Choroidal blood flow
Intervention measure
作者简介
通信作者:王华。E⁃mail:wanghuaeye@163.com
